Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu +6 more
wiley +2 more sources
Effects of Glyphosate on the Planktonic Microbiota: An Experimental Approach
ABSTRACT Glyphosate is one of the most widely used herbicides in the world, including in Brazil, and its dispersion through habitats and surface waters can impact entire aquatic ecosystems. However, experimental studies evaluating the effects of pesticides on whole planktonic communities, considering attributes such as richness, density and composition—
Melissa Progênio +7 more
wiley +1 more source
Photodynamic inactivation of <i>Staphylococcus aureus</i> with rose bengal reduces superantigen activity. [PDF]
Ogonowska P +4 more
europepmc +1 more source
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim +6 more
wiley +1 more source
Rose Bengal-Incorporated Supramolecular Gels as a Topical Platform for Localized Antimicrobial Photodynamic Therapy. [PDF]
Anguluri K +6 more
europepmc +1 more source
The new Cu‐containing MOF (Me2NH2)(CuICl2)@[Cu4(INA)4Cl2O]·1.5dmf (3) contains a cation and an anion as guests and shows UV‐near‐mid‐IR absorption and near‐IR emission. MOF 3 shows gas‐solid reactivity in the presence of NH3 and HCOOH to yield two new 3D MOF.
Rajat Saha +10 more
wiley +1 more source
Rose Bengal-Assisted Photodynamic Antimicrobial Therapy for Keratitis. [PDF]
Roy A, Kompella UB.
europepmc +1 more source
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang +12 more
wiley +1 more source
Green combustion synthesis of monoclinic Bi₂₆Mo₁₀O₆₉ nanoparticles using simarouba glauca leaves for efficient visible-light-driven photocatalytic degradation of Rose Bengal dye. [PDF]
Puttaswamy S +4 more
europepmc +1 more source
Corneal Resistance to Enzymatic Digestion After Rose Bengal and Combined Rose Bengal/Riboflavin Cross-Linking Is Oxygen Independent. [PDF]
Aydemir ME +6 more
europepmc +1 more source

