Results 41 to 50 of about 998,275 (297)

The impact of different rose bengal formulations on corneal thickness and the efficacy of rose bengal/green light corneal cross-linking in the rabbit eye [PDF]

, 2022
PURPOSE:To examine central corneal thickness (CCT) changes during in vivo rose bengal-green light corneal cross-linking (RG-CXL) and compare the CXL efficacy of different rose bengal formulations.
Hayes, Sally, Shengnan Ding, Huang, Jinhai, Keith M. Meek, Li, Junhua, Ding, Shengnan, Xueyang Chen, Yan, Mengdi, Rongrong Gao, Chen, Ming, Huang, Yuyan, He, Huanhuan, Junhua Li, Xu, Wenjin, Huanhuan He, Yuyan Huang, Jinhai Huang, Shixiang Yan, Mengdi Yan, Wenjin Xu, Sally Hayes, Gao, Rongrong, Qinmei Wang, Chen, Xueyang, Ming Chen, Meek, Keith M., Yan, Shixiang, Wang, Qinmei   +27 more
core   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Comparison of Fluorescein and Rose Bengal Staining

Ophthalmology, 1992
The authors have recently reported that rose bengal is not a vital dye, and stains whenever the cultured cells are not covered by such components as albumin and mucin, and such a tear substitute as carboxycellulose. In this report, using cultured cells as well as normal rabbit corneas, they characterize and correlate the staining differences between ...
R P, Feenstra, S C, Tseng
openaire   +2 more sources

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Photoinactivation of Escherichia coli using xanthene dyes and light-emitting diodes

Brazilian Dental Science, 2010
The development of antibiotic resistance by pathogenic bacteria is currently one of the major problems in medicine. Therefore, the study of new treatment modalities such as photodynamic therapy is important.
Rodnei Dennis Rossoni, Simone Furgeri Godinho Vilela, Lilibeth Ferraz Brito Penna Forte, Antonio Olavo Cardoso Jorge, Juliana Campos Junqueira   +4 more
doaj   +1 more source

Photoinactivation of Vaccinia Virus with Rose Bengal

Journal of General Virology, 1968
Summary Photoinactivation of vaccinia virus was complete but slower with rose bengal than with methylene blue as the sensitizing dye. Photoinactivation was inhibited and changes in dye absorption spectra occurred when protein but not when nucleic acid was added to rose bengal + virus mixtures; with methylene blue + virus mixtures nucleic aid but not ...
G S, Turner, C, Kaplan
openaire   +2 more sources

Carrier‐Free Stimulus‐Responsive Theranostic Nanoprodrug Enabling GSH‐Consumption‐Promoted Chemo‐Photodynamic Cancer Therapy

Advanced Science, EarlyView.
Leveraging the critical role of glutathione (GSH) in mediating drug resistance and scavenging reactive oxygen species (ROS) in cancer cells, a carrier‐free GSH‐consuming theranostic nanoprodrug, consisting of a BODIPY photosensitizer and the chemotherapeutic drug paclitaxel linked through a GSH‐consuming drug linker, is developed to deeply explore the ...
Hansheng Huang, Binglin Sui
wiley   +1 more source

Brucellosis Seroprevalance in Inonu University Medical Faculty Hospital: The Results of Rose Bengal, Wright, Coombs Aglutination Tests

Medicine Science, 2013
This study aimed to determine the seroprevalence of brucellosis in our region. Serological markers (Wright, Coombs agglutination test and Rose-Bengal test) of brucellosis, were evaluated retrospectively according to laboratory data for 2942 sera from ...
Yucel Duman, Mehmet Sait Tekerekoglu, Nihal Secil Bati, Baris Otlu   +3 more
doaj   +1 more source