Results 201 to 210 of about 722,005 (275)

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

open access: yesChemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih   +6 more
wiley   +1 more source

A Self‐Supervised Framework for Space Object Behaviour Characterisation

open access: yesExpert Systems, Volume 43, Issue 10, October 2026.
ABSTRACT Foundation Models, which leverage large neural networks pre‐trained on unlabelled data before fine‐tuning for specific tasks, are increasingly being applied to specialised domains. Recent examples include ClimaX for climate and Clay for satellite Earth observation, but a Foundation Model for Space Object Behavioural Analysis (SOBA) has not yet
Ian Groves   +6 more
wiley   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

open access: yesChemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande   +6 more
wiley   +1 more source

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