Results 231 to 240 of about 451,327 (295)

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Oxygen‐Mediated Fe‐N3O Single‐Atom Sites Enabled by Lignin‐Derived Hierarchical Carbon for Efficient Oxygen Reduction

Advanced Science, EarlyView.
A cooperative dual‐template strategy transforms oxygen‐rich lignin into hierarchical porous carbon hosting asymmetric Fe‐N3O single‐atom sites. The unique coordination downshifts the Fe d‐band center, weakening *OOH adsorption and accelerating charge transfer.
Xuhong Zheng, Yukun Luo, Mengxuan Zhang, Xuebin Lv, Tianguang Wang, Jing Gu, Kang Xiao, Zhaoqing Liu, Haoran Yuan, Gaixiu Yang   +9 more
wiley   +1 more source

Continuous Extraction of Europium(III) by Ionic Liquid in the Rotating Disk Column with an Asymmetrical Structure Aimed at the Evaluation of Reactive Mass Transfer. [PDF]

ACS Omega, 2020
Asadollahzadeh M, Torkaman R, Torab-Mostaedi M.   +2 more
europepmc   +1 more source

An Integrated Framework Coupling Hierarchical Hyperspectral i‐trait Screening, Gene Identification, and Functional Validation for Genetic Dissection of Salt Tolerance in Cotton

Advanced Science, EarlyView.
An integrated phenomics–genomics framework captures dynamic salt‐stress responses in laboratory‐grown cotton seedlings through time‐series hyperspectral imaging and non‐destructive i‐trait extraction. Hierarchical screening identifies biologically relevant, heritable, and non‐redundant traits for high‐resolution GWAS, identifying GhST7.
Bowei Xu, Le Liu, Mengli Yu, Yuling Guo, Junli Ye, Jun Zhang, Rumeng Zhao, Jiajie Yang, Wanneng Yang, Yameng Xu, Liqiang Fan, Zuoren Yang   +11 more
wiley   +1 more source

Surface‐Selective Pt Enrichment for Stabilizing Ultrathin 2D PtCu Nanosheets Toward Durable Oxygen Reduction

Advanced Science, EarlyView.
Ultrathin 2D alloy nanosheet catalysts could offer exceptional catalytic activity but suffer from severe structural instability. Here, a surface‐selective Pt enrichment strategy via galvanic replacement effectively stabilizes PtCu Nanosheets while preserving their ∼ 1 nm thickness and (111) facets.
HyunWoo J. Yang, SangJae Lee, KwangHo Lee, HyunWoo Chang, HyunWoo T. Yang, Dongwon Shin, MinJun Kim, EunAe Cho   +7 more
wiley   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu, Sheng‐Jie Chang, Xiao‐Wei Liu, Shu‐Bao Zhang, Ying‐Jie Wang, Shan‐Jin Wang   +5 more
wiley   +1 more source

Piezoelectric Amino Acid Salts with Halogen‐Based Coformers Produce Exceptional Force‐Generated Voltage Output

Advanced Science, EarlyView.
Amino acid‐based multicomponent crystals have emerged as high‐performance, environmentally sustainable piezoelectrics. In this work, the correlation of crystal packing, molecular polarization, and electromechanical response is uncovered through integrated experimental and computational approaches.
Krishna Hari, Shubham Vishnoi, Sarah Guerin   +2 more
wiley   +1 more source

Surface‐State‐Driven Selectivity of Electrocatalytic Glucose Oxidation: Metallic Au, Au─OH, and CuO

Advanced Science, EarlyView.
In the electrochemical oxidation of glucose, whether the pyranose ring opens upon adsorption decides the reaction pathway: ring opening on metallic Au yields gluconic acid, gluconolactone formation on Au─OH leads to glucaric acid, and C─C cleavage on CuO gives formic acid. Surface state thus governs product selectivity.
Myeonghwan Oh, Hoeun Seong, Ga Eun Jo, Jiyoung Hwang, Yurim Sohn, Kyoungsuk Jin, Jong Hyeok Park, Wooyul Kim, Seok Ki Kim, Dong Ki Lee   +9 more
wiley   +1 more source

Gd‐Mediated Spin‐State Modulation of Co Sites Enhances Oxygen Electrocatalysis in Zn‐Air Battery

Advanced Science, EarlyView.
The Gd‐mediated spin‐state modulation strategy was proposed to enhance electrocatalytic performance of Co sites towards oxygen reduction reaction. The Gd incorporation modulates the local electronic structure of Co centers by inducing pronounced spin splitting and orbital‐selective spin polarization, which optimizes the adsorption of oxygen‐containing ...
Yijie Shen, Yu Zhu, Tianrui Zhao, Yiwen An, Xuan Wang, Meng Li, Dongmei Sun, Linda Zhang, Hao Li, Yawen Tang, Gengtao Fu   +10 more
wiley   +1 more source

Microenvironment‐Responsive Biomimetic Hydrogels Delivering Cistanche Deserticola‐Derived Nanovesicles for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
An injectable, microenvironment‐responsive hydrogel (HAPOCS@CDNVs) is developed for sustained delivery of Cistanche deserticola‐derived nanovesicles (CDNVs). By scavenging ROS, restoring mitochondrial function, and attenuating SASP, this platform effectively suppresses nucleus pulposus cell senescence and facilitates extracellular matrix reconstruction,
Ning Xu, Xiaoyu Cai, Xiaofu Tang, Weidong Liang, Linsong Teng, Yudong Jing, Haifeng Hu, Yuhao Duan, Mingjie Kuang, Lei Zhang, Shijie Han, Weibin Sheng   +11 more
wiley   +1 more source