Results 241 to 250 of about 1,439,489 (335)

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

open access: yesAdvanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li   +14 more
wiley   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

open access: yesAdvanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen   +9 more
wiley   +1 more source

An Automated and Miniaturized Rotating-Disk Device for Rapid Nucleic Acid Extraction. [PDF]

open access: yesMicromachines (Basel), 2019
Tong R   +10 more
europepmc   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang   +18 more
wiley   +1 more source

Micro/Nanoscale Acoustic Manipulation: From Particle Control to Autonomous Microswimmers

open access: yesAdvanced Science, EarlyView.
This conceptual framework illustrates acoustic technology as a multifunctional platform enabling passive particle manipulation across scales and autonomous propulsion of microswimmers. ABSTRACT Acoustic manipulation and propulsion technologies have emerged as powerful platforms for micro/nanoscale control, enabled by their non‐contact operation, label ...
Jiahui Chu   +4 more
wiley   +1 more source

Nanocluster‐Assisted OH Ligand Modification Optimizes Activity and Stability of Fe‐N‐C Catalysts

open access: yesAdvanced Science, EarlyView.
A nanocluster‐assisted ligand engineering stabilizes OH‐modified FeN4 active sites through strong electronic coupling between isolated Fe atoms and adjacent nanoclusters. This synergy optimizes oxygen‐intermediate adsorption, lowers ORR energy barriers, and breaks the conventional activity–stability trade‐off, enabling high ORR activity, exceptional ...
Xue Zhao   +6 more
wiley   +1 more source

ROTATING BIOLOGICAL DISKS

open access: yesJournal of the Agricultural Engineering Society, Japan, 1986
openaire   +1 more source

Tri‐Functional Electrocatalysis for Zinc–Air Battery Coupled Water Splitting: A Catalyst‐Electrode‐Device‐System Perspective

open access: yesAdvanced Science, EarlyView.
This review establishes a catalyst–electrode–device–system framework for tri‐functional HER/OER/ORR electrocatalysis that couples water splitting with Zn–air batteries. Five catalyst families are covered: noble‐metal, metal‐based, single‐atom, heterostructure, and metal‐free systems.
Xixi Di   +9 more
wiley   +1 more source

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