Results 171 to 180 of about 17,434 (263)

Furfuryl Alcohol‐Driven Proton Supply Enables Efficient Photocatalytic H2O2 Production Beyond Water‐Based Systems

open access: yesAdvanced Science, EarlyView.
A ZnIn2S4–carbon dot heterojunction enables photocatalytic H2O2 production coupled with furfuryl alcohol oxidation. In this redox system, furfuryl alcohol acts as both the electron donor and oxidation substrate, producing furoic acid with 100% selectivity and 98% conversion while supporting efficient H2O2 generation with a solar‐to‐chemical conversion (
Pengfei Bai   +9 more
wiley   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Reconstruction of Ultrafine MnS‐Induced Vacancy‐Rich Co9S6.29 Precatalysts in Mesoporous S‐Doped N‐Rich Hollow Carbon Nanotubes Enables Dynamic O‐Vacancy Cycling for High‐Performance Zn‐Air Batteries

open access: yesAdvanced Science, EarlyView.
We develop vacancy‐rich Co9S6.29 precatalysts formed via ultrafine MnS‐induced lattice distortion in mesoporous S‐doped N‐rich hollow carbon nanotubes (CM@SNHCTs). This CM@SNHCT precatalyst is reconstructed into catalytically‐active cathode phases that enable efficient oxygen reduction/evolution reactions (ORR/OER) through dynamic O‐vacancy formation ...
Debarani Devi Khumujam   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy