Results 51 to 60 of about 1,878 (261)

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Gas Turbine Aerodynamics Improvement Via a Design of Intelligent Fractional Control

Journal of Mechanical Engineering, 2021
Gas turbines are complex processes characterized by the instability and uncertainty of various sources. The range of useful operating in an axial compressor which is part of a turbine gas is limited by aerodynamic instabilities that are surge and ...
Abdesselam Debbah, Hamid Kherfane, Ridha Kelaiaia   +2 more
doaj   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Rotating Stall Inception Prediction Using an Eigenvalue-Based Global Instability Analysis Method

International Journal of Turbomachinery, Propulsion and Power
The accurate prediction of rotating stall inception is critical for determining the stable operating regime of a compressor. Among the two widely accepted pathways to stall, namely, modal and spike, the former is plausibly believed to originate from a ...
Shenren Xu, Caijia Yuan, Chen He, Dongming Cao, Dakun Sun, Carlos Martel, Huihao Chen, Dingxi Wang   +7 more
doaj   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Observations of the Growth and Decay of Stall Cells during Stall and Surge in an Axial Compressor

International Journal of Rotating Machinery, 2017
This research investigated unsteady events such as stall inception, stall-cell development, and surge. Stall is characterized by a decrease in overall pressure rise and nonaxisymmetric throughflow.
Adam R. Hickman, Scott C. Morris
doaj   +1 more source

Numerical Investigation of Rotating Stall Characteristics and Active Stall Control in Centrifugal Compressors

Volume 2: Simple and Combined Cycles; Advanced Energy Systems and Renewables (Wind, Solar and Geothermal); Energy Water Nexus; Thermal Hydraulics and CFD; Nuclear Plant Design, Licensing and Construction; Performance Testing and Performance Test Codes; Student Paper Competition, 2014
This paper focuses on providing better view for the understanding of rotating stall phenomenon in centrifugal compressors by using numerical simulations and presents a study of the role of air injection method in delaying stall inception by using different injection parameters aiming at increasing the efficiency of this method.
Halawa, Taher, Alqaradawi, Mohamed, Badr, Osama, Gadala, Mohamed S.   +3 more
openaire   +2 more sources

Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping

Advanced Science, EarlyView.
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron, Bokun Zheng, Ziyang Zhou, Noel Naughton, Suyi Li   +4 more
wiley   +1 more source

Analysis of Geometries' Effects on Rotating Stall in Vaneless Diffuser with Wavelet Neural Networks

International Journal of Rotating Machinery, 2007
Wavelet neural network (WNN), which combines the capability of neural network in learning from process and that of wavelet decomposition, was used to study geometry factors on rotating stall in vaneless diffusers.
Chuang Gao, Chuangang Gu, Tong Wang, Bo Yang   +3 more
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source