Results 51 to 60 of about 49,011 (121)

Health and Survival Impacts of Early Childhood Development Programmes: The Case of the Happy Child Programme in Brazil

Review of Development Economics, EarlyView.
ABSTRACT This paper adds to the growing evidence on the impacts of early childhood development (ECD) programming by examining one of the world's largest home visitation programmes, the Happy Child Programme in Brazil, and its impacts on child vaccination and preventable death rates.
Raquel Tebaldi, Franziska Gassmann, Bruno Martorano   +2 more
wiley   +1 more source

Preclinical and clinical development of preventive rotavirus vaccines: special considerations

Биопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Vaccination is recognised as the only effective method for preventing rotavirus disease. Rotavirus remains a leading cause of death in young children, mainly, in developing countries.
A. S. Korovkin, D. V. Gorenkov, A. A. Soldatov, V. A. Merkulov   +3 more
doaj   +1 more source

The effects of nosocomial rotavirus gastroenteritis on the length of hospital stay and cost

Journal of Infection in Developing Countries, 2016
Introduction: In this study, the goal was to evaluate the impact of nosocomial rotavirus gastroenteritis in pediatric patients by determining the incidence of nosocomial rotavirus gastroenteritis, the resulting duration of hospital stay, and direct cost.
Özlem O Gundeslioglu, Recep Tekin, Saliha Cevik, Yılmaz Palancı, Atilla Yazıcıoglu   +4 more
doaj   +1 more source

Candidate New Rotavirus Species in Sheltered Dogs, Hungary

Emerging Infectious Diseases, 2015
We identified unusual rotavirus strains in fecal specimens from sheltered dogs in Hungary by viral metagenomics. The novel rotavirus species displayed limited genome sequence homology to representatives of the 8 rotavirus species, A–H, and qualifies as a
Eszter Mihalov-Kovács, Ákos Gellért, Szilvia Marton, Szilvia L. Farkas, Enikő Fehér, Miklós Oldal, Ferenc Jakab, Vito Martella, Krisztián Bányai   +8 more
doaj   +1 more source

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun, Nicole Hammann, Lina Leghlam, Bianca Peters, Cigdem Arikan, Sarah M. Bedoyan, Qian Chen, Tal Dattner, Felix Distelmaier, Alexander Fichtner, Sven F. Garbade, Nedim Hadžić, Robert Hegarty, Andrea Hellwig, Marianne Hørby Jørgensen, Carolin Jentsch, Sabine Jung‐Klawitter, Martin Laass, Elke Lainka, Hannah Münch, Halise Neslihan Önenli Mungan, Moritz Niesert, Stephanie Oehrl, Begona Polo, Knut Schäkel, James E. Squires, Stefan Kölker, Georg F. Hoffmann, Christian Staufner, Dominic Lenz   +29 more
wiley   +1 more source

JAK Inhibition in PNPT1‐Related Mitochondrial Interferonopathy: A Case Report and Review of Mitochondrial–Immune Crosstalk

JIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Biallelic pathogenic variants in PNPT1 cause combined oxidative phosphorylation deficiency 13 (COXPD13) (MIM #614932), linking mitochondrial dysfunction to type I interferon (IFN) activation through cytosolic leakage of mitochondrial double‐stranded RNA (mt‐dsRNA).
Dan Ross Brooks, Hyun Yong Koh, Taylor Martin Kerrins, Steven Lang, Emily Bland, Rui Yang, Sarah Kogan Nicholas, Stephanie Jean Sikkink, Stephen Kralik, Christine Eng, Chaya Nautiyal Murali, Seema Lalani, Pilar Lenglet Magoulas, Lisa Emrick, Kristen Sydney Fisher, Fernando Scaglia   +15 more
wiley   +1 more source

Hypertransaminasemia Is a Marker of Severity in Children Hospitalized for Influenza

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Purpose Elevated transaminases have been associated with increased severity in adult influenza cases, but data in the pediatric population are limited. This study aims to evaluate the prevalence, clinical characteristics and prognostic value of elevated transaminases in children hospitalized for influenza.
Marco Poeta, Cristina Moracas, Elisabetta Venturini, Sofia Sgubbi, Maria Sole Valentino, Laura Folgori, Laura Petrarca, Claudio Cafagno, Marco Maglione, Anna Cascone, Claudia Colomba, Alice Romero, Fabio Midulla, Giuseppe Indolfi, Vania Giacomet, Amelia Licari, Luisa Galli, Alfredo Guarino   +17 more
wiley   +1 more source

Beyond Hemostasis: Platelet Biomarkers and Vascular‐Immune Crosstalk in Dengue

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Several biomarkers are associated with platelet activation during dengue virus (DENV) infection. These include serum markers (AST, ALT, ferritin), platelet surface or secreted molecules (P‐selectin, PF4, RANTES, VEGF‐A, CD40L, TREM‐1, TLT‐1), immune and endothelial markers (TREM‐1, Ang‐1, Ang‐2), and viral components such as DENV EIII.
Amanda Beatriz Adriano da Silva‐Alencar, Amanda de Oliveira Matos, Daniel Francisco de Sousa, Jefferson do Carmo Dietz, Eugenio Damaceno Hottz, Marcelle Figueira Marques da Silva‐Sales, Helioswilton Sales‐Campos   +6 more
wiley   +1 more source

Epidemiologia das infecções por rotavírus no Brasil e os desafios para o seu controle

Cadernos de Saúde Pública, 2000
Os rotavírus causam de 600.000 a 870.000 óbitos por ano entre crianças em todo o mundo. Esses vírus foram visualizados pela primeira vez no Brasil em 1976, a partir da microscopia eletrônica das fezes de crianças diarréicas em Belém, Pará.
Linhares Alexandre C.
doaj  

Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice

Viruses
The leading cause of gastroenteritis in children under the age of five is rotavirus infection, accounting for 37% of diarrhoeal deaths in infants and young children globally.
Sarah Woodyear, Tawny L. Chandler, Takahiro Kawagishi, Tom M. Lonergan, Vanshika A. Patel, Caitlin A. Williams, Sallie R. Permar, Siyuan Ding, Sarah L. Caddy   +8 more
doaj   +1 more source