Results 21 to 30 of about 51,266 (182)

A Novel Rotavirus Reverse Genetics Platform Supports Flexible Insertion of Exogenous Genes and Enables Rapid Development of a High-Throughput Neutralization Assay

Viruses, 2023
Despite the success of rotavirus vaccines, rotaviruses remain one of the leading causes of diarrheal diseases, resulting in significant childhood morbidity and mortality, especially in low- and middle-income countries. The reverse genetics system enables
Jiajie Wei, Scott Radcliffe, Amanda Pirrone, Meiqing Lu, Yuan Li, Jason Cassaday, William Newhard, Gwendolyn J. Heidecker, William A. Rose II, Xi He, Daniel Freed, Michael Citron, Amy Espeseth, Dai Wang   +13 more
doaj   +1 more source

Epidemiological aspects, diagnosis and prevention of rotaviral infection

One Health & Risk Management, 2021
Introduction. Diarrheal diseases are the leading cause of childhood mortality globally as well as in Republic Moldova. Rotavirus has been recognized as the most common cause of infectious gastroenteritis in infants and young children.
Ahmad Adnan SALTI
doaj  

Deployment of Rotavirus Vaccine in Western Kenya Coincides with a Reduction in All-Cause Child Mortality: A Retrospective Cohort Study

Vaccines, 2023
Rotavirus is an important cause of fatal pediatric diarrhea worldwide. Many national immunization programs began adding rotavirus vaccine following a 2009 World Health Organization recommendation.
Peter Sifuna, Andrea V. Shaw, Tina Lucas, Bernards Ogutu, Walter Otieno, David A. Larsen   +5 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Detection of Rotavirus and Enteric Adenovirus Frequency In Children with Acute Gastroenteritis Attending to Our Hospital: A Sivas-Scale Retrospective Study

, 2021
Objectives: Viral gastroenteritis is a major health problem that is common worldwide, especially in developing countries, and is responsible for the majority of childhood diarrhea disease.
TAŞKIN KAFA, AYŞE HÜMEYRA, Ayşe Hümeyra TAŞKIN KAFA, Çelik, Cem, Cem ÇELİK, Hasbek, Mürşit, Taşkın Kafa, Ayşe Hümeyra, Mürşit HASBEK   +6 more
core   +1 more source

Epidemiological Survey of Rotaviruses Responsible for Infantile Diarrhea by the Immunomolecular Technique in Cotonou (Benin, West Africa)

International Journal of Microbiology, 2018
Rotavirus remains the main causative agent of gastroenteritis in young children, in countries that have not yet introduced the vaccine. Benin, in order to implement the WHO recommendations, projects to introduce the rotavirus vaccine in 2018 as part of ...
Jijoho Mischaël Michel Agbla, Annick Capo-Chichi, Alidéhou Jerrold Agbankpé, Tamègnon Victorien Dougnon, Anges William M. Yadouleton, Olivia Houngbégnon, Clément Glele-Kakai, George Enyimah Armah, Honoré Bankolé   +8 more
doaj   +1 more source

Rotavirus structure, genomics, types, pathophysiology and prevention: Review Article [PDF]

Zagazig University Medical Journal
Children under the age of five are most commonly affected by severe, dehydrating gastroenteritis brought on by infections with rotavirus. Despite the common usage of rotavirus immunizations more than ten years ago, rotavirus infections still cause more ...
Ensaf Azzazy, Ghada Abdellatif, Hala Abd-ElMoneim Mohamed, Doaa Abo-Alella   +3 more
doaj   +1 more source

Study the Distribution of Rotavirus Genotypes in Vaccinated and non Vaccinated Children in Babylon Province

Iraqi Journal of Pharmaceutical Sciences, 2021
Rotaviruses, a major cause of gastroenteritis in children worldwide accounts for around half a million deaths annually. Vaccine against the virus has been recommended by the WHO to be involved in the national immunization program.To evaluate the genetic ...
Qassim Mahdi Mutlak, Manal Khalid Abdulridha, Laith M Abbas Al-Huseini   +2 more
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Rotavirus infections and their genotype distribution in Rwanda before and after the introduction of rotavirus vaccination

PLoS ONE, 2023
Rotavirus vaccination has reduced mortality and hospital admissions due to rotavirus diarrhoea, but its effect on rotavirus infections and the impact of rotavirus genotypes are still unclear. Real-time PCR was used to detect rotavirus and other pathogens
Jean-Claude Kabayiza, Staffan Nilsson, Maria Andersson   +2 more
doaj