Results 181 to 190 of about 64,554 (238)
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Rotavirus

Infection Control, 1987
Acute gastroenteritis is a public health problem of global proportions. Worldwide there are more than 700 million cases of diarrheal disease resulting in around 5 million deaths. In the United States the incidence of acute gastroenteritis is 11% each year and it is second only to respiratory infection as a contagious disease in the American family. The
J T, Sinnott, M R, Cancio
openaire   +2 more sources

Rotavirus

Baillière's Clinical Gastroenterology, 1990
Since their discovery in the 1970s, the human rotaviruses have been recognized as the most important cause of acute infectious gastroenteritis among infants and children worldwide. Rotavirus has been found to infect almost all mammalian and avian species tested, and is primarily a disease of the young.
Y A, Maldonado, R H, Yolken
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Rotavirus

Clinics in Laboratory Medicine, 2015
Group A rotavirus (RVA) is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live, attenuated rotavirus vaccines, Rotarix® and RotaTeq®, has dramatically reduced RVA-associated AGE and mortality. High-throughput, sensitive and specific techniques are required to rapidly diagnose and characterize rotavirus ...
Mathew D, Esona, Rashi, Gautam
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Rotavirus and Rotavirus Vaccines

2006
Two new rotavirus vaccines have recently been licensed that will provide the intervention needed to diminish the huge burden of rotavirus disease among all children. In many upper and middle income countries, these vaccines will soon be available for the routine immunization of children.
Roger I, Glass   +5 more
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Impact of rotavirus vaccines on rotavirus disease

Expert Review of Anti-infective Therapy, 2012
Rotaviruses are the most common cause of acute gastroenteritis in young children worldwide. Both licensed rotavirus vaccines (Rotarix™ [RV1] and RotaTeq™ [RV5]) are effective and safe. Studies from countries that have included RV1 or RV5 in the national immunization programs have demonstrated their safety and sustained efficacy under real-life ...
Lepage, Philippe, Vergison, Anne
openaire   +3 more sources

Rotavirus vaccines

Current Opinion in Infectious Diseases, 2000
The past few years have seen important developments in understanding the epidemiological and virological characteristics of rotaviruses, and rapid progress has been made in rotavirus vaccine development, but further challenges remain before a vaccine is introduced into widespread use.
Maureen, Lynch   +3 more
openaire   +2 more sources

Rotavirus

Clinics in Laboratory Medicine, 1999
Rotavirus is the leading cause of nonbacterial gastroenteritis in young children and may infect neonates, older children, and adults as well. A large number of serogroups and types complicates the study, epidemiology, diagnosis, and prevention of rotaviral illness. Currently, routine diagnostic methods are satisfactory only for group A rotaviruses, and
openaire   +2 more sources

Rotavirus vaccines

Scandinavian Journal of Infectious Diseases, 2008
Two live attenuated oral rotavirus vaccines were licensed in 2006 for prevention of severe acute gastroenteritis in children: Rotarix (GSK), a human rotavirus vaccine with G1P[8] serotype characteristics and RotaTeq (Merck), a bovine-human reassortant vaccine expressing human G1-4 and P[8] antigens.
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Rotavirus Antigens

1985
The rotaviruses are important medical and veterinary pathogens that cause acute diarrheal disease in children and in the young of most mammalian and avian species. The successful development of a rotavirus vaccine should significantly reduce worldwide infant morbidity and mortality and economic losses and increase food-production.
M K, Estes, D Y, Graham
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