Results 11 to 20 of about 23,321 (196)

Incidence and clinical characteristics of group A rotavirus infections among children admitted to hospital in Kilifi, Kenya. [PDF]

PLoS Medicine, 2008
BackgroundRotavirus, predominantly of group A, is a major cause of severe diarrhoea worldwide, with the greatest burden falling on young children living in less-developed countries. Vaccines directed against this virus have shown promise in recent trials,
D James Nokes, John Abwao, Allan Pamba, Ina Peenze, John Dewar, J Kamino Maghenda, Hellen Gatakaa, Evasius Bauni, J Anthony G Scott, Kathryn Maitland, Thomas N Williams   +10 more
doaj   +2 more sources

Rotavirus [PDF]

Emerging Infectious Diseases, 1998
Rotavirus, the most common diarrheal pathogen in children worldwide, causes approximately one third of diarrhea-associated hospitalizations and 800,000 deaths per year. Because natural infection reduces the incidence and severity of subsequent episodes, rotavirus diarrhea might be controlled through vaccination.
Umesh D. Parashar, Joseph S. Bresee, Jon R. Gentsch, Roger I. Glass   +3 more
openaire   +3 more sources

Rotavirus and autoimmunity [PDF]

Journal of Infection, 2020
Rotavirus, a major etiological agent of acute diarrhea in children worldwide, has historically been linked to autoimmunity. In the last few years, several physiopathological approaches have been proposed to explain the leading mechanism triggering autoimmunity, from the old concept of molecular mimicry to the emerging theory of bystander activation and
J, Gómez-Rial, I, Rivero-Calle, A, Salas, F, Martinón-Torres   +3 more
openaire   +2 more sources

Rotavirus

Microbiology Spectrum, 2013
ABSTRACTRotaviruses (RV) are ubiquitous, highly infectious, segmented double-stranded RNA genome viruses of importance in public health because of the severe acute gastroenteritis they cause in young children and many animal species. They are very well adapted to their host, with symptomatic and asymptomatic reinfections being virtually universal ...
Franco, Manuel A., Greenberg, Harry B.
openaire   +3 more sources

Putative E3 Ubiquitin Ligase of Human Rotavirus Inhibits NF-κB Activation by Using Molecular Mimicry To Target β-TrCP

mBio, 2015
NF-κB plays a critical role in the induction and maintenance of innate and adaptive immune transcriptional programs. An associated inhibitor of κB protein (IκB) regulates NF-κB activation and contains a degron motif (DSGΦxS) that undergoes ...
Marco Morelli, Allison F. Dennis, John T. Patton   +2 more
doaj   +1 more source

Seroepidemiology of group A rotavirus in suburban São Paulo, Brazil [PDF]

, 1998
Age-specifc patterns of rotavirus infection were investigated using a randomly selected and representative sample of sera from a suburban community of São Paulo, Brazil screened for class-specifc antibodies to group A rotavirus.
Cox, M. J., Beards, G. M., Massad, Eduardo, Medley, Graham, Nokes, D. James, Azevedo, R. S., McCrae, Malcolm A.   +6 more
core   +1 more source

Rotavirus gastroenteritis in children hospitalized in northeastern Poland in 2006–2020: Severity, seasonal trends, and impact of immunization

International Journal of Infectious Diseases, 2021
Objectives: The introduction of the rotavirus vaccine in 2006 significantly reduced childhood incidence of acute gastroenteritis (AGE) worldwide. The rotavirus vaccine was included in Poland’s national immunization program in 2021.
Kacper Toczylowski, Katarzyna Jackowska, Dawid Lewandowski, Sandra Kurylonek, Marlena Waszkiewicz-Stojda, Artur Sulik   +5 more
doaj   +1 more source

Household Transmission of Rotavirus in a Community with Rotavirus Vaccination in Quininde, Ecuador [PDF]

, 2013
Background: We studied the transmission of rotavirus infection in households in peri-urban Ecuador in the vaccination era. Methods: Stool samples were collected from household contacts of child rotavirus cases, diarrhea controls and healthy controls ...
Martha Chico, Daniel Payne, Payne, Daniel, Ben Lopman (41533), Michael D. Bowen, Vicuña, Y, Esona, Matthew D., Chico, Martha, Fabian Salazar, Lopman, B, Sandoval, C, Bowen, MD, Nely Broncano, Nicole Gregoricus, Vicuña Yosselin, Vaca, Martiza, Ben Lopman, Chico, M, Martha Chico (270482), Yosselin Vicuña (432014), Vaca, M, Yosselin Vicuña, Broncano Nely, Umesh Parashar, Payne Daniel, Matthew D Esona, Gregoricus, N, Cooper, PJ, Cooper, Philip, Vicuña, Yosselin, Parashar Umesh, Broncano, Nely, Broncano, N, Fabian Salazar (432015), Carlos Sandoval (314735), Chico Martha, Nely Broncano (218294), Esona, MD, Michael D Bowen, Nicole Gregoricus (161222), Salazar, F, Gregoricus Nicole, Parashar, U, Matthew D. Esona, Daniel Payne (432018), Michael D. Bowen (432017), Salazar Fabian, Martiza Vaca (432019), Parashar, Umesh, Payne, D, Philip J. Cooper, Carlos Sandoval, Matthew D. Esona (432016), Umesh Parashar (432020), Gregoricus, Nicole, Cooper Philip J., Salazar, Fabian, Bowen, Michael D., Philip J. Cooper (218309), Esona Matthew D., Bowen Michael D., Sandoval, Carlos, Lopman Ben, Lopman, Ben, Sandoval Carlos, Vaca Martiza, Philip J Cooper, Martiza Vaca   +67 more
core   +2 more sources

Rotavirus specific maternal antibodies and immune response to RV3-BB neonatal rotavirus vaccine in New Zealand

Human Vaccines & Immunotherapeutics, 2017
Background: Maternal antibodies, acquired passively via placenta and/or breast milk, may contribute to the reduced efficacy of oral rotavirus vaccines observed in children in developing countries.
Mee-Yew Chen, Carl D. Kirkwood, Julie Bines, Daniel Cowley, Daniel Pavlic, Katherine J. Lee, Francesca Orsini, Emma Watts, Graeme Barnes, Margaret Danchin   +9 more
doaj   +1 more source

Genotypic characterization of rotavirus in children under 5 years circulating in Côte D’Ivoire from 2010 to 2013

Virology Journal, 2018
Background Rotavirus infection is the most common cause of severe gastroenteritis in children under five years of age in both developed and developing countries.
Catherine Boni-cisse, Sindou Meite, Alice Britoh Mlan, Flore Zaba, Rebecca N’Guessan, Nicaise Aka Lepri, Bélinda Lartey   +6 more
doaj   +1 more source