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Infectious Disease Clinics of North America, 2012
Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and continues to have a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavirus disease.
Penelope H. Dennehy, Penelope H. Dennehy
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Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and continues to have a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavirus disease.
Penelope H. Dennehy, Penelope H. Dennehy
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Rotavirus infection and prevention
Current Opinion in Pediatrics, 1997The major advance in knowledge about rotavirus infection and prevention has been in vaccine development. Several large studies of tetravalent rhesis rotavirus vaccine have had encouraging results, and a first-generation vaccine is likely to be licensed by the 25th anniversary of the discovery of rotavirus (in 1973).
Graeme L. Barnes, Ruth F. Bishop
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Detection and control of rotavirus infections in zoo animals.
Journal of the American Veterinary Medical Association, 1983Fecal specimens from 15 exotic animal species, with and without diarrhea, were examined for the presence of rotavirus, bacterial enteropathogens, and intestinal parasites.
B. M. Baumeister +3 more
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Clinical Infectious Diseases, 1991
Rotavirus (RV) infections in newborns differ from those in older infants; the majority of RV infections that occur in neonates are mild or asymptomatic. Generally, fewer than one-third of RV-infected neonates have diarrhea, although rates have reached 77% in some hospital nursery populations. Cases with severe diarrhea, necrotizing enterocolitis, bowel
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Rotavirus (RV) infections in newborns differ from those in older infants; the majority of RV infections that occur in neonates are mild or asymptomatic. Generally, fewer than one-third of RV-infected neonates have diarrhea, although rates have reached 77% in some hospital nursery populations. Cases with severe diarrhea, necrotizing enterocolitis, bowel
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Epidemiology of rotavirus infections in The Netherlands
Acta Paediatrica, 1999This paper reviews published and unpublished data from epidemiological and virological studies or rotavirus in the Netherlands to identify gaps in our knowledg; it includes analysis of surveillance data for seasonality and age groups at risk.
Koopmans, M, van Asperen, I
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Expert Review of Anti-infective Therapy, 2007
A new paradigm of rotavirus disease is emerging and rotavirus infection is no longer considered to be localized and confined to the GI tract. New evidence indicates that rotavirus infection is systemic. Viral antigen and infectious virus frequently enter the circulation in both children and animal model systems.
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A new paradigm of rotavirus disease is emerging and rotavirus infection is no longer considered to be localized and confined to the GI tract. New evidence indicates that rotavirus infection is systemic. Viral antigen and infectious virus frequently enter the circulation in both children and animal model systems.
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Rotavirus Infection in a Geriatric Population
Archives of Internal Medicine, 1982An outbreak of gastroenteritis affected 19 of 34 geriatric patients and four of 23 staff assigned to the ward in a period of 3 1/2 weeks in January 1980. Fourteen of the 19 patients with gastroenteritis (17 were tested properly) and four of the ten asymptomatic patients (five asymptomatic patients were not tested) showed evidence of rotavirus infection
James Ethier +4 more
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Epidemiology of rotavirus infection in Thailand
Pediatrics International, 2000Abstract Rotavirus is a major cause of acute severe diarrhea in children worldwide and an important cause of death among young children in developing countries. Group A rotaviruses are antigenically complex and multiple serotypes infect humans. Reassortant rotavirus vaccines are now available which offer protection against severe illness caused by ...
Niwat Maneekarn, Hiroshi Ushijima
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Effect of enzymes on rotavirus infectivity
Journal of Clinical Microbiology, 1979The infectivity of a bovine rotavirus was enhanced 140-, 8-, and 3-fold, respectively, by trypsin, protease, and lactase. Ficin, carboxypeptidases A and B, lysozyme, and beta-galactosidase had little effect on the infectivity. Chymotrypsin caused a threefold decrease in the infectivity. Trypsin acts directly on the rotavirus and not on the host cell.
M L Clark, B B Barnett, R S Spendlove
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Rotavirus infection in children in Japan
Pediatrics International, 2000Abstract Currently, a high morbidity of rotavirus diarrhea has been seen in children in developed and developing countries. Improvement of the vaccines is necessary in order to reduce the burden of diarrhea caused by rotavirus. A survey of rotavirus infection from diarrheal stool specimens in children of seven regions in Japan was conducted from 1984 ...
Kunio Kaneshi +10 more
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