Results 111 to 120 of about 293,907 (269)

Borate driven heterogeneous networks for porous elastomers with improved tribological and mechanical performances

open access: yesNature Communications
Porous polydimethylsiloxane (PDMS) elastomers produced using conventional phase separation methods often suffer from limited tribological and mechanical properties.
Yuhao Wu   +13 more
doaj   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

open access: yesAdvanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu   +9 more
wiley   +1 more source

Intrinsic Superprotonic Conduction in Metal‐Free Hydrogen‐Bonded Organic–Inorganic Frameworks

open access: yesAdvanced Science, EarlyView.
A simple hybridization strategy yields a suite of metal‐free hydrogen‐bonded organic‐inorganic frameworks (HOIFs) with dense, uninterrupted hydrogen‐bonded networks that possess intrinsically high superprotonic conductivity, establishing a versatile and scalable platform for high‐performance solid‐state proton conductors.
Jin Chen   +14 more
wiley   +1 more source

Full Annular RUB in Mechanical Seals, Part I: Experimental Results

open access: yesInternational Journal of Rotating Machinery, 2002
Donald E. Bently   +3 more
doaj   +1 more source

Analytical modeling of rotor-structure coupling using modal decomposition for the structure and the blades. [PDF]

open access: yes, 2014
This paper presents a linear semi-analytical model that is able to predict complex rotor-structure coupling phenomena and their stability. It was primarily designed so as to gain a better physical understanding of this kind of aeroelastic instabilities ...
ROUCOULES, Lionel   +3 more
core  

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

open access: yesAdvanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie   +24 more
wiley   +1 more source

Field‐Driven Active Colloids as Distributed Micromachines: Bridging Physics, Control, and Function Across Length Scales

open access: yesAdvanced Science, EarlyView.
Field‐driven active colloids are framed as distributed micromachines in which externally supplied power, sensing, and control regulate task‐relevant states. By closing the loop between particle behavior, imaging, computation, and electric or magnetic actuation, these systems can progress from programmable motion toward adaptive functional outcomes ...
Ruchi Patel, Bhuvnesh Bharti
wiley   +1 more source

The Cytoplasmic MicroRNA‐Production Complex Regulates MicroRNA Sorting to Extracellular Vesicles During Synaptogenesis

open access: yesAdvanced Science, EarlyView.
The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng   +6 more
wiley   +1 more source

Lactate‐H3K18la‐RPL11 Axis Drives Gemcitabine Resistance in Pancreatic Cancer by Integrating Protein Synthesis and DNA Damage Repair

open access: yesAdvanced Science, EarlyView.
A lactate‐H3K18la epigenetic axis upregulates RPL11 to drive gemcitabine resistance in pancreatic cancer. RPL11 orchestrates chemoresistance through a dual, compartmentalized role: enhancing cytoplasmic protein synthesis via EEF1A1 stabilization and promoting nuclear DNA damage repair by co‐activating PARP14, thus ensuring robust cell survival ...
Lijun Zhao   +10 more
wiley   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang   +6 more
wiley   +1 more source

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