Results 101 to 110 of about 152,300 (313)

Coupled rotor-body equations of motion hover flight [PDF]

A set of linearized equations of motion to predict the linearized dynamic response of a single rotor helicopter in a hover trim condition to cyclic pitch control inputs is described.
Curtiss, H. C., Jr., Mckillip, R. M., Jr.   +1 more
core   +1 more source

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

Active control and system identification of rotordynamic structure [PDF]

Four current research projects are summarized: (1) active control of rotor system dynamics; (2) attenuation of rotor vibration using controlled pressure hydrostatic bearings; (3) a new seal test facility for measuring isotropic and anisotropic linear ...
Adams, M. L.
core   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Analytical and experimental study of vibrations in a gear transmission [PDF]

An analytical simulation of the dynamics of a gear transmission system is presented and compared to experimental results from a gear noise test rig at the NASA Lewis Research Center. The analytical procedure developed couples the dynamic behaviors of the
Choy, F. K., Coy, J. J., Oswald, Fred B., Ruan, Y. F., Zakrajsek, J. J.   +4 more
core   +1 more source

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

Advanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar, Jonas Bosche, Mirko Wieczorek, Constantin Matteo Albrecht, Belinda König, Mona Grünewald, Ludger Santen, Stefan Diez, Reza Shaebani, Laura Schaedel   +9 more
wiley   +1 more source

Counter Rotating Open Rotor Animation using Particle Image Velocimetry

, 2011
This article describes the two accompanying fluid dynamics videos for the "Counter rotating open rotor flow field investigation using stereoscopic Particle Image Velocimetry" presented at the 64th Annual Meeting of the APS Division of Fluid Dynamics in ...
Agocs, J., Geisler, R., Neitzke, K. -P., Pallek, D., Roosenboom, E. W. M., Schroeder, A.   +5 more
core  

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Verification of aero-engine numerical rotor models based on virtual static structural and modal tests

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
A method for developing a numerical rotor model and its further verification based on the results of virtual static structural and modal tests was proposed.
K. V. Shaposhnikov, S. A. Degtyarev, M. K. Leontiev, S. V. Anisimov   +3 more
doaj   +1 more source

Explanation of the onset of bouncing cycles in isotropic rotor dynamics; a grazing bifurcation analysis. [PDF]

Proc Math Phys Eng Sci, 2020
Mora K, Champneys AR, Shaw AD, Friswell MI.   +3 more
europepmc   +1 more source