Results 81 to 90 of about 1,333,451 (280)

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Regionale keringen Rotterdam: Overstromingsrisico's en strategieën

, 2014
Het programma Rotterdam Climate Proof en het Waterplan Rotterdam richten zich op het klimaatbestendig maken van de stad en haar omgeving. In dat kader is voor het thema waterveiligheid onderzoek verricht naar de klimaatbestendigheid van de regionale ...
Van Barneveld, N. (author), Weeda, A. (author), De Moel, H. (author)   +2 more
core  

Combating ESG Greenwashing Through AI Models: Evidence From Disaggregated AI Technologies, Mechanisms, and Thresholds

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines how artificial intelligence language models influence corporate environmental, social, and governance greenwashing (GWESG$$ {\mathrm{GW}}_{\mathrm{ESG}} $$) behavior, utilizing panel data from Chinese listed firms spanning 2012–2022.
Brahim Bergougui, Hamid Ghazi H. Sulimany, Abdulrahman Atllah Alharbi   +2 more
wiley   +1 more source

Firm‐Level Corporate Social Responsibility and Employees' Affective Outcomes: A Multilevel Approach

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study advances research on corporate social responsibility (CSR) and employees' work attitudes by distinguishing between employee‐level CSR perceptions and firm‐level CSR practices. Prior research has mainly focused on how employees' perceptions of CSR relate to their affective outcomes; this study extends that perspective by jointly ...
Alexander C. Kraaij, Agnieszka Paruzel, Arnoud de Jong   +2 more
wiley   +1 more source

Port Accessibility Depends on Cascading Interactions between Fleets, Policies, Infrastructure, and Hydrodynamics

Journal of Marine Science and Engineering
Reducing waiting times is crucial for ports to be efficient and competitive. Important causes of waiting times are cascading interactions between realistic hydrodynamics, accessibility policies, vessel-priority rules, and detailed berth availability. The
Floor P. Bakker, Solange van der Werff, Fedor Baart, Alex Kirichek, Sander de Jong, Mark van Koningsveld   +5 more
doaj   +1 more source

Rotterdam Pascalweg-Catullusweg

, 2017
Algemeen In opdracht van het Ingenieursbureau van Gemeentewerken Rotterdam heeft het Bureau Oudheidkundig Onderzoek van Gemeentewerken Rotterdam (BOOR) in februari 2011 een verkennend inventariserend veldonderzoek uitgevoerd in het plangebied Rotterdam ...
Schiltmans, drs. D.E.A. (Gemeente Rotterdam), Meer, drs. A. van de (Gemeente Rotterdam)   +1 more
core   +1 more source

BOORrapporten 712

, 2020
In opdracht van Leyten Vastgoedontwikkeling II BV heeft het team Onderzoek en Rapportage van Archeologie Rotterdam op 28 oktober 2020 een verkennend inventariserend veldonderzoek uitgevoerd in het plangebied Prins Alexanderpolder Hoofdweg 260 in de ...
Berg, drs S van den (Archeologie Rotterdam)
core   +1 more source

Towards Transformative Climate Governance: Capacities and Constraints for Local Government in Aotearoa New Zealand

Environmental Policy and Governance, EarlyView.
ABSTRACT An emerging consensus calls for transformative climate governance. However, what instigates and sustains transformative pathways remains unclear. This study characterises the existence, quality and structural underpinnings of transformative governance capacities in local government climate change response in Aotearoa New Zealand, applying a ...
Gangadari K. Ranawaka, Anna L. Berka, Karen F. Hytten, Florentine D. van Noppen   +3 more
wiley   +1 more source

BOORrapporten 691

, 2020
Algemeen In opdracht van Stadsontwikkeling Rotterdam heeft het team Onderzoek en Rapportage van Archeologie Rotterdam op 20 en 21 januari, 24 tot en met 27 februari en 26 mei 2020 een verkennend inventariserend veldonderzoek uitgevoerd in het plangebied ...
Berg, drs. S. van den (Archeologie Rotterdam), Ploegaert, drs. P.H.J.I. (Archeologie Rotterdam)   +1 more
core   +1 more source

Unraveling the Interplay Between Collaborative Governance and Experimentation for Transformative Potential in Circular Water Systems: A Dutch Case Study

Environmental Policy and Governance, EarlyView.
ABSTRACT Freshwater availability is a critical climate change challenge in coastal delta regions. This challenge requires a transformative change toward circular water management. While experimentation and collaborative governance are recognized as enablers of transformative change, their interaction remains complex and insufficiently understood ...
Flavia Simona Albu Cosoveanu, Kirsty Holstead, Jean‐Marie Buijs, Dave Huitema   +3 more
wiley   +1 more source