Results 171 to 180 of about 21,573 (293)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Effects of anisotropy in rough fractures on flow behavior and solute migration

工程科学与技术
Objective Fractures serve as the primary pathways for groundwater flow and major storage spaces in geological media. Groundwater flow and solute transport in fractured media typically demonstrate nonlinear and anisotropic characteristics.
QIN Jinyue, DENG Yinger, LI Pengjie, CHEN Tongtong   +3 more
doaj  

Laser-Assisted Diamond Turning for Anisotropy Suppression in Calcium Fluoride. [PDF]

Micromachines (Basel)
Xing E, Xue J, Yang R, Wang M, Zhou H, Xing G, Li J, Rong J, Wen H, Tang J, Liu J.   +10 more
europepmc   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

The Effect of Microstructural Evolution on Mechanical Behavior of Carbon/Carbon Composites After Heat Treatment. [PDF]

Materials (Basel)
Yuan Z, Liu X, Yang Y.
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Local shear mechanical behavior of rock joint under constant normal load. [PDF]

Sci Rep
Wang W, Ma H, Dai C, Qian J.
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Degradation of biodegradable orthopedic screws does (not) elevate tissue heating under Magnetic Resonance Imaging: Implications for next generation implants. [PDF]

Bioact Mater
Berangi M, Waiczies H, Saha N, Shalikar S, Majd MS, Niendorf T.   +5 more
europepmc   +1 more source

Invasion flow enhanced solute mixing at rough-walled rock fracture intersections [Elektronisk resurs]

The processes of fluid flow and solute transport through rock fractures are of primary importance in environmental engineering and geosciences. This study presented numerical modeling results of fluid flow and solute transport in a 3D rock fracture ...
Zou, Liangchao,, Jing, Lanru,, Cvetkovic, Vladimir,   +2 more
core