Results 31 to 40 of about 5,871,393 (260)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Training set edition using Rough Set Theory for Semi-supervised Classification

open access: yes, 2017
Semi-supervised Classification (SSC) is becoming an attractive research filed due to the emergence of real-world problems on which the number of unlabeled examples exceeds the labeled ones.
Nápoles, G.   +4 more
core   +2 more sources

Rough set theory and its applications

open access: yesJournal of Telecommunications and Information Technology, 2002
In this paper rudiments of the theory will be outlined, and basic concepts of the theory will be illustrated by a simple tutorial example, concerning churn modeling in telecommunications.
Zdzisław Pawlak
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

More on neutrosophic soft rough sets and its modification [PDF]

open access: yesNeutrosophic Sets and Systems, 2015
This paper aims to introduce and discuss anew mathematical tool for dealing with uncertainties, which is a combination of neutrosophic sets, soft sets and rough sets, namely neutrosophic soft rough set model. Also, its modification is introduced. Some of
Emad Marei
doaj  

On the significance of form induced stress in rough wall turbulent boundary layers [PDF]

open access: yes, 2008
This paper presents a review of recent experimental and numerical studies which deal with the analysis of form-induced stress in rough wall turbulent boundary layers.
Costantino Manes   +20 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Constructing a Hoop Using Rough Filters

open access: yesBulletin of the Section of Logic, 2022
When it comes to making decisions in vague problems, rough is one of the best tools to help analyzers. So based on rough and hoop concepts, two kinds of approximations (Lower and Upper) for filters in hoops are defined, and then some properties of them ...
Rajab Ali Borzooei, Elham Babaei
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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