Results 41 to 50 of about 52,011 (260)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Two kinds of average approximation accuracy

CAAI Transactions on Intelligence Technology
Rough set theory places great importance on approximation accuracy, which is used to gauge how well a rough set model describes a target concept. However, traditional approximation accuracy has limitations since it varies with changes in the target ...
Qingzhao Kong, Wanting Wang, Dongxiao Zhang, Wenbin Zhang   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Kernel Neighborhood Rough Sets Model and Its Application

Complexity, 2018
Rough set theory has been successfully applied to many fields, such as data mining, pattern recognition, and machine learning. Kernel rough sets and neighborhood rough sets are two important models that differ in terms of granulation.
Kai Zeng, Siyuan Jing
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Multigranulation rough set: A multiset based strategy

International Journal of Computational Intelligence Systems, 2017
A simple multigranulation rough set approach is to approximate the target through a family of binary relations. Optimistic and pessimistic multigranulation rough sets are two typical examples of such approach.
Xibei Yang, Suping Xu, Huili Dou, Xiaoning Song, Hualong Yu, Jingyu Yang   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Matrix-Based Approaches for Updating Approximations in Multigranulation Rough Set While Adding and Deleting Attributes

International Journal of Computational Intelligence Systems
With advanced technology in medicine and biology, data sets containing information could be huge and complex that sometimes are difficult to handle. Dynamic computing is an efficient approach to solve some problems. Since multigranulation rough sets were
Peiqiu Yu, Jinjin Li, Hongkun Wang, Guoping Lin   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

DEDEKIND-MACNEILLE COMPLETION OF THE ROUGH SETS SYSTEM AS PASTING OF ROUGH APPROXIMATION LATTICES [PDF]

Journal of Algebraic Systems
The pattern of embedding of rough approximation lattices defined by a reflexive relation in its Dedekind-MacNeille completion of rough sets system is taken up for study in this work.The reflexive relation R for which the Dedekind-MacNeille completion of ...
Umadevi Dwaragan
doaj   +1 more source