Results 181 to 190 of about 3,575,082 (253)

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

Advanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun, Rohan Narayan, Santhosh Kambaiah Nagaraj, Rishad Shiraz, Abinaya Kaliappan, Sumandeep Kaur, Ankur Singh, Siva Shanmugam Selvaraj, Gudepalya Renukaiah Rudramurthy, Chakenahalli Naveenkumar, Shridhar Narayanan, Radha Krishan Shandil, Shailly Tomar, Shashank Tripathi   +13 more
wiley   +1 more source

A Ten-Gene Transcriptomic Biomarker Panel for Glioma Classification and Prognosis Identified via Integrative Hypergraph and Rough Set Analysis. [PDF]

Cancers (Basel)
Akgüller Ö, Balcı MA, Cioca G.
europepmc   +1 more source

Poloxamer‐Enabled Thermoresponsive Biobased Controlled‐Release Fertilizer for On‐Demand Nutrient Delivery

Advanced Science, EarlyView.
A bio‑based thermoresponsive controlled‑release fertilizer (TRBF) is fabricated by introducing F127 into a castor‑oil‑derived polyurethane coating. Distinct from conventional bio‑based coated fertilizer (BCF), TRBF achieves temperature‑regulated nitrogen release via F127 reversible phase transition, suppressing nutrient leakage at low temperature and ...
Jiahui Liu, Junyin Li, Ziyao Li, Xiangjie Zhao, Fengyan Fang, Yan Liu, Songyuan Wang, Boning Su, Yuanyuan Yao, Bin Gao, Shugang Zhang, Yuechao Yang   +11 more
wiley   +1 more source

A semi-analytical physics-informed neural network framework with hessian analysis for singularly perturbed fractal convection-dominated anomalous diffusion problems. [PDF]

MethodsX
Jha N, Rai MB.
europepmc   +1 more source

Multifunctional Vertical Bulk‐Heterojunction Transistors With Amorphous GaOx for Neuromorphic Perception‐to‐Decision

Advanced Science, EarlyView.
A multifunctional vertical bulk‐heterojunction transistor (MVBT) with amorphous GaOx integrates four functionalities within a single neuromorphic device. Gate‐source operation enables 254 nm deep‐ultraviolet sensing and threshold neuronal firing, whereas three‐terminal operation supports broadband UV–vis‐NIR synaptic functions and bias‐controlled ...
Jinkui Si, Qiong Zhuang, Rengjian Yu, Junling Zhou, Lan Yang, Changjie Zhou, Huili Zhu, Minshuai Wang, Xiaomei Cai, Qiubao Lin, Wangying Xu, Shuqiong Lan, Huipeng Chen   +12 more
wiley   +1 more source

An Ultrastructural and Proteomic Analysis in DM1 Young Adults' Myoblasts: Stressed RER and Mitochondrial Dysfunction Involvement. [PDF]

J Cell Mol Med
Del Carratore R, Falleni A, Bernardeschi M, Frenzilli G, Ripolone M, Salani S, Geraci F, Miraglia F, Del Seppia C.   +8 more
europepmc   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

Advanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim, Gyunghyun Jang, Seungwon Jin, Jaewon An, Dongbin Shin, Hyeon‐Jin Shin, Jie Luo, Akel Hashim, Irfan Siddiqi, Yosep Kim, Long B. Nguyen, Hoon Hahn Yoon   +11 more
wiley   +1 more source

A Hybrid ISSA-XGBoost Model for Predicting Wellbore Leakage. [PDF]

Sensors (Basel)
Bai K, Chen J, Yin S, Wei C, Yan Y, Liu J.   +5 more
europepmc   +1 more source

The Potential of Zero Charge: An Interfacial Descriptor Governing Hydrogen Evolution Reaction on Bulk Metal Electrodes

Advanced Science, EarlyView.
This work establishes a dual‐descriptor framework incorporating hydrogen adsorption free energy and potential of zero charge, constructing a corrected 3D HER volcano plot. It reveals that surface charge and interfacial proton concentration jointly govern activity, beyond conventional 2D thermodynamic scaling relations. ABSTRACT While the Sabatier‐based
Yuefei Zhang, Yufei Xue, Yang Zhang, Xuefei Liu, Aijun Du, Lin‐wang Wang, Guoping Gao   +6 more
wiley   +1 more source

CRISP: Enhancing ASE Workflows With Advanced Molecular Simulation Post-Processing. [PDF]

J Comput Chem
Saha I, Willimetz D, Grajciar L.
europepmc   +1 more source