Results 151 to 160 of about 909,546 (299)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Additional file 2 of A non-randomized, open-label study to assess the impact of rounds of mass drug administration with artemisinin-piperaquine plus primaquine on malaria in São Tomé Island

Additional file 2.
Li, Mingqiang, Tan, Ruixiang, Chen, Peiting, Rampao, Herodes Sacramento, D’almeida, Carlos Alberto Bandeira, Li, Guoming, Liu, Jingwen, Shi, Guozhuang, Chen, Fei, Shu, Lei, Huang, Xinan, Deng, Changsheng, Guo, Wenfeng, Song, Jianping   +13 more
openaire   +1 more source

Effects of the private-label invasion in food industries [PDF]

Using supermarket scanner data, we test a variety of hypotheses from trade journals about the invasion of private-label food products. According to conventional industry wisdom, name-brand firms defended their brands against new private-label products by
Ward, Michael B., Perloff, Jeffrey M., Shimshack, Jay P., Harris, J. Michael   +3 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Additional file 3 of A non-randomized, open-label study to assess the impact of rounds of mass drug administration with artemisinin-piperaquine plus primaquine on malaria in São Tomé Island

Additional file 3.
Li, Mingqiang, Tan, Ruixiang, Chen, Peiting, Rampao, Herodes Sacramento, D’almeida, Carlos Alberto Bandeira, Li, Guoming, Liu, Jingwen, Shi, Guozhuang, Chen, Fei, Shu, Lei, Huang, Xinan, Deng, Changsheng, Guo, Wenfeng, Song, Jianping   +13 more
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

RETHINKING SELF-DISTILLATION: LABEL AVERAGING AND ENHANCED SOFT LABEL REFINEMENT WITH PARTIAL LABELS

We investigate the mechanisms of self-distillation in multi-class classification, particularly in the context of linear probing with fixed feature extractors where traditional feature learning explanations do not apply.
Chung, Hye Won, Jeong, Hyeonsu
core   +1 more source

NT Youth Round Table

, 2016
Chief Minister's Round Table of Young ...

core   +1 more source

Additional file 5 of A non-randomized, open-label study to assess the impact of rounds of mass drug administration with artemisinin-piperaquine plus primaquine on malaria in São Tomé Island

Additional file 5.
Li, Mingqiang, Tan, Ruixiang, Chen, Peiting, Rampao, Herodes Sacramento, D’almeida, Carlos Alberto Bandeira, Li, Guoming, Liu, Jingwen, Shi, Guozhuang, Chen, Fei, Shu, Lei, Huang, Xinan, Deng, Changsheng, Guo, Wenfeng, Song, Jianping   +13 more
openaire   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source