Results 151 to 160 of about 3,039,505 (287)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

European Union trade mark round-up 2019

Journal of Intellectual Property Law & Practice, 2020
David Rogers, Arnaud Folliard-Monguiral
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Ocular adnexal plasmacytoma presenting as a lesion of the plica semilunaris and caruncle in a 21-year-old male. [PDF]

Am J Ophthalmol Case Rep
Al-Kaylani HM, Torres G, Holman CJ, Binkley E, Greiner MA, Goins KM, Smith MC, Syed NA, Matharu KS.   +8 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Consensus on the Content of an Instrument to Assess Psychological Distress Following Multifetal Pregnancy Reduction: A Delphi Study. [PDF]

Nurs Open
Xu J, Li Q, Wen H, Ye C, Peng G.
europepmc   +1 more source

Mark Tucci and Doc Morgan, Amateur Golf Tournament, both scored 69 in first round, as well as two other players, Bloomington, IL 1962

Mark Tucci and Doc Morgan, Amateur Golf Tournament, both scored 69 in first round, as well as two other players, Bloomington, IL ...
Simpson, Bob
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Urban gardens foster year-round activity of bumble bee queens. [PDF]

Ecology
Finn SR, Erickson E, Crone EE.
europepmc   +1 more source

Round-up of non-traditional EU trade mark decisions in 2021

Journal of Intellectual Property Law & Practice, 2022
Gordon Humphreys, Nedim Malovic, Stefan Martin   +2 more
openaire   +1 more source