Results 61 to 70 of about 3,039,505 (287)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Migration confers winter survival benefits in a partially migratory songbird
eLife, 2017 To evolve and to be maintained, seasonal migration, despite its risks, has to yield fitness benefits compared with year-round residency. Empirical data supporting this prediction have remained elusive in the bird literature.
Daniel Zúñiga +7 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Method of vibration diagnostics of pre-emergency conditions in technogenic and natural objects
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. The purpose of the study is to develop a method for measuring vibrations based on the analysis of images of a round-shaped test fragment with vibration blur by measuring the direction of vibration of the surface element of the test object ...
A.V. Grigoryev
doaj +1 more source
Carroll Round Proceedings 2015
, 2015 Undergraduate economic research papers presented at the 10th Annual Carroll Round Conference at Georgetown ...
Carroll Round
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Corela, 2011 In the field of morphology, it has been known for a long time that derivation precedes inflexion, and not the other way round (Greenberg 1963: 83).
Pierre-Yves Kersulec
doaj +1 more source
Carroll Round Proceedings 2008
, 2008 Undergraduate economic research papers presented at the sixth annual Carroll Round Research ...
Carroll Round
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
When it comes round to marking assignments: how to impress and how to ‘distress’ lecturers …
Assessment & Evaluation in Higher Education, 2009 What do lecturers look for when marking essays? What impresses them and what frustrates them? In this paper, we present the results of a survey which asked lecturers to address these questions. Thirty‐two lecturers responded to an email survey in which they listed the problems they found most frustrating when marking essays and the factors which most ...
Greasley, Pete, Cassidy, Andrea
openaire +3 more sources