Comparison of Subjective Responses to Oral and Intravenous Alcohol Administration under Similar Systemic Exposures [PDF]
Objective To test whether an individual's subjective responses to alcohol are similar when the breath alcohol concentration (BrAC) trajectory resulting from oral administration is matched by intravenous administration.
Boes, Julian +6 more
core +1 more source
Nasal Drug Delivery Systems: An Overview [PDF]
Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R. +3 more
core +1 more source
Efficacy/Safety of the Use of Glucocorticoids in Oral and Maxillofacial Surgery
Introduction: Glucocorticoids, also known as corticosteroids or steroids, are drugs derived from cholesterol. They are synthesized by the adrenal cortex, along with other hormones, such as cortisol and aldosterone.
Heilyn Joanna Nils +4 more
doaj +1 more source
Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats [PDF]
The aim of this work was to study in rats the nasal route for the brain delivery of the vasoactive intestinal peptide (VIP) neuropeptide. After evaluating VIP stability in solutions obtained from nasal washes, the effect of formulation parameters (pH 4-9,
Couet, William +5 more
core +3 more sources
Characteristics of the antibiotic regimen that affect antimicrobial resistance in urinary pathogens
Background Treatment duration, treatment interval, formulation and type of antimicrobial (antibiotic) are modifiable factors that will influence antimicrobial selection pressure.
Boudewijn Catry +5 more
doaj +1 more source
Cannabis and COVID-19: Reasons for Concern
The lockdown measures implemented to curb the spread of SARS-CoV-2 may affect (illicit) drug consumption patterns. This rapid response study investigated changes in cannabis use in a non-probability sample of cannabis users in the Netherlands during the ...
Margriet W. van Laar +5 more
doaj +1 more source
Progesterone – a new look at an old drug
On the basis of the literature the role of progesterone in contemporary medicine was described, having regard to different routes of administration. Review of the available literature on the role of progesterone in modern obstetric practice says that ...
Малгожата Зыгмунт +1 more
doaj +1 more source
Stroke is one of the leading causes of death and disability worldwide, so there is an urgent need to find a therapy for the tragic outcomes of this cerebrovascular disease.
Andrea Valeri, Emanuela Mazzon
doaj +1 more source
Distribution and Excretion of TEGDMA in Guinea Pigs and Mice [PDF]
The monomer triethyleneglycoldimethacrylate (TEGDMA) is used as a diluent in many resin-based dental materials. It was previously shown in vitro that TEGDMA was released into the adjacent biophase from such materials during the first days after placement.
A. Jewett +15 more
core +1 more source
A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis [PDF]
© Queen’s Printer and Controller of HMSO 2013Severe allergic rhinitis uncontrolled by conventional medication can substantially affect quality of life. Immunotherapy involves administering increasing doses of a specific allergen, with the aim of reducing
Barton, P +7 more
core +1 more source

