Results 111 to 120 of about 1,377,003 (377)

Admission dental examination: protocol and its importance in the diagnosis of oral pathology

Brazilian Journal of Oral Sciences, 2015
The aim of this paper is to describe an efficient clinical protocol used in admittance dental examinations, highlighting the importance of this evaluation in the diagnosis of oral pathologies.
Mário Marques Fernandes, Mara Rosângeles de Oliveira, Rafael Bender Carpena de Menezes de Oliveira, Talita Lima de Castro, Luiz Renato Paranhos, Eduado Daruge Júnior   +5 more
doaj   +1 more source

Getting antimalarials on target: impact of national roll-out of malaria rapid diagnostic tests on health facility treatment in three regions of Tanzania

Tropical medicine & international health, 2013
Parasitological confirmation of malaria prior to treatment is recommended for patients of all ages, with malaria rapid diagnostic tests (mRDTs) an important tool to target artemisinin‐based combination therapies (ACTs) to patients with malaria.
Katia J. Bruxvoort, A. Kalolella, H. Nchimbi, Charles Festo, Mark Taylor, R. Thomson, M. Cairns, J. Thwing, I. Kleinschmidt, C. Goodman, S. Kachur   +10 more
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

The development of a machine learning algorithm for early detection of viral hepatitis B infection in Nigerian patients

Scientific Reports, 2023
Access to Hepatitis B Virus (HBV) testing for people in low-resource settings has long been challenging due to the gold standard, enzyme immunoassay, being prohibitively expensive, and requiring specialised skills and facilities that are not readily ...
Busayo I. Ajuwon, Alice Richardson, Katrina Roper, Meru Sheel, Rosemary Audu, Babatunde L. Salako, Matthew O. Bojuwoye, Ibraheem A. Katibi, Brett A. Lidbury   +8 more
doaj   +1 more source

Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ [PDF]

, 2017
In this issue of Clinical Science, Biesbroek and colleagues describe recent work on magnetic resonance imaging (MRI)-based cerebral lesion location and its association with cognitive decline.
McCleery, Jenny, Quinn, Terence J.
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Transient elastography improves detection of liver cirrhosis compared to routine screening tests.

World Journal of Gastroenterology, 2015
AIM To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound.
T. Göbel, Janine Schadewaldt-Tümmers, L. Greiner, C. Poremba, D. Häussinger, A. Erhardt   +5 more
semanticscholar   +1 more source

Testing for ARCH in the Presence of Nonlinearity of Unknown Form in the Conditional Mean [PDF]

Tests of ARCH are a routine diagnostic in empirical econometric and financial analysis. However, it is well known that misspecification of the conditional mean may lead to spurious rejections of the null hypothesis of no ARCH.
Andrew P. Blake, George Kapetanios
core  

Release of Mast Cell Tryptase into Saliva: A Tool to Diagnose Food Allergy by a Mucosal Challenge Test? [PDF]

, 2011
Background: Our aim was to examine whether measurement of the saliva mast cell tryptase (MCT) concentrations before and after a mucosal challenge test with the offending food would be helpful in diagnosing food allergy.
Alexander Arnold, Ali FR, Bacon AS, Bernhard Przybilla, Franziska Ruëff, Kramer MF, Margrini L, Matthias Kramer, Niedoszytko M, Sommerhoff CP, Svensson C, Tanja Friedl   +11 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source