Results 111 to 120 of about 592,995 (349)

Reduced amplification efficiency of the RNA-dependent-RNA-polymerase target enables tracking of the Delta SARS-CoV-2 variant using routine diagnostic tests. [PDF]

J Virol Methods, 2022
Valley-Omar Z, Marais G, Iranzadeh A, Naidoo M, Korsman S, Maponga T, Hussey H, Davies MA, Boulle A, Doolabh D, Laubscher M, Wojno J, Deetlefs JD, Maritz J, Scott L, Msomi N, Naicker C, Tegally H, de Oliveira T, Bhiman J, Williamson C, Preiser W, Hardie D, Hsiao NY.   +23 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

A review of evidence on non-invasive prenatal diagnosis (NIPD) : tests for fetal RHD genotype [PDF]

, 2007
This report concentrates on three main areas. First and foremost, we set the background context for RhD NIPD in prenatal care. While the methodology chapter describes how the literature review was carried out and how additional information was collected,
Clay, Diane, Freeman, Karoline, HASH(0x55aa091d4640), Hyde, Julia, Osipenko, Leeza, Szczepura, Ala   +5 more
core  

Getting antimalarials on target: impact of national roll-out of malaria rapid diagnostic tests on health facility treatment in three regions of Tanzania. [PDF]

, 2013
OBJECTIVES: Parasitological confirmation of malaria prior to treatment is recommended for patients of all ages, with malaria rapid diagnostic tests (mRDTs) an important tool to target artemisinin-based combination therapies (ACTs) to patients with ...
Bruxvoort, Katia, Cairns, Matthew, Festo, Charles, Goodman, Catherine, Kachur, S Patrick, Kalolella, Admirabilis, Kleinschmidt, Immo, Nchimbi, Happy, Taylor, Mark, Thomson, Rebecca, Thwing, Julie   +10 more
core   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Accuracy of Malaria Rapid Diagnostic Tests in Community Studies and their Impact on Treatment of Malaria in an Area with Declining Malaria Burden in North-Eastern Tanzania. [PDF]

, 2011
Despite some problems related to accuracy and applicability of malaria rapid diagnostic tests (RDTs), they are currently the best option in areas with limited laboratory services for improving case management through parasitological diagnosis and ...
A Enevold, A Laurent, A Moody, AB Ly, BP Mmbando, BP Mmbando, Bruno P Mmbando, C Sayang, CA Petti, CI Chandler, CK Murray, CM Zikusooka, D Bell, D Bell, D Bell, Deus S Ishengoma, DJ Kyabayinze, DJ Kyabayinze, DR Ishengoma, DR Ishengoma, EK Ansah, Filbert Francis, H Hopkins, H Reyburn, H Reyburn, I Bates, Ib C Bygbjerg, J Bendezu, J Chinkhumba, John PA Lusingu, JP Lusingu, JP Lusingu, M Alifrangis, Martha M Lemnge, MI Msellem, Michael Alifrangis, Ministry of Health, ML McMorrow, ML McMorrow, MM Lemnge, N Singh, P Mens, Pamela Magistrado, R Development Core Team. R, RN Bronzan, S Gerstl, TA Abeku, Thor G Theander, V Batwala, V D'Acremont, WHO, WHO, WP O'Meara, Z Bisoffi, Z Bisoffi   +54 more
core   +4 more sources

Predicting Malnutrition Risk with Data from Routinely Measured Clinical Biochemical Diagnostic Tests in Free-Living Older Populations [PDF]

, 2021
Saskia P. M. Truijen, Richard Hayhoe, Lee Hooper, Inez Schoenmakers, Alastair Forbes, Ailsa Welch   +5 more
openalex   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

People's perception of malaria in Mbarara, Uganda.

, 2002
To understand people's perceptions of malaria and their implications for control programmes, we held focus group discussions (FGDs) and conducted semi-structured interviews (SSIs) with community members in Mbarara, Uganda.
Nuwaha, Fred
core   +1 more source

A comparison of cognitive function, sleep and activity levels in disease-free breast cancer patients with or without cancer-related fatigue syndrome. [PDF]

, 2012
Chronic fatigue is a feature in a subset of women successfully treated for breast cancer but is not well characterised. This study examines differences in objective cognitive function, activity levels and sleep in disease-free women who do and do not ...
Minton, O, Stone, PC
core   +1 more source