Results 121 to 130 of about 1,377,003 (377)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Performance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study

BMC Infectious Diseases
Background Limited literature exists on the diagnostic yield of traditional and molecular tuberculosis (TB) tests using bronchoalveolar lavage (BAL) specimens in high burden South American countries. The aim of the study is to determine the value of acid-
Vanessa Sabella-Jiménez, Valentina L. Sabella-Jiménez, Valentina Restrepo-Espinosa, Juanita Eljadue-Flórez, Claredit Valentina Gallardo-Castro, Andrea Alexandra Silvera, Carlos Otero-Herrera, Hugo Andrés Macareno Arroyo, Jorge Acosta-Reyes, Jorge Luis Quintero Barrios   +9 more
doaj   +1 more source

How can malaria rapid diagnostic tests achieve their potential? A qualitative study of a trial at health facilities in Ghana. [PDF]

, 2010
BACKGROUND: Rapid diagnostic tests (RDTs) for malaria are at the early stages of introduction across malaria endemic countries. This is central to efforts to decrease malaria overdiagnosis and the consequent overuse of valuable anti-malarials and ...
Ansah, Evelyn K, Chandler, Clare IR, Whitty, Christopher JM   +2 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Frequency and indication of non-musculoskeletal examinations: a cross-sectional survey of Quebec chiropractors

Chiropractic & Manual Therapies
Background Approximately 1% of low back pain is estimated to be caused by serious systemic diseases, including cancer, infection, or abdominal aortic dissection.
Danikel Giroux, Chloé Branconnier, André Bussières, Jean Théroux, Marc-André Blanchette   +4 more
doaj   +1 more source

Epidemiology, impact and control of bovine cysticercosis in Europe : a systematic review [PDF]

, 2016
Background: Bovine cysticercosis in Europe has been known for centuries but the data showing the occurrence of this zoonosis are scarce. The aim of this paper is to review and present the current knowledge on bovine cysticercosis in Europe.
Allepuz, Alberto, Devleesschauwer, Brecht, Dorny, Pierre, Gabriël, Sarah, Laranjo-González, Minerva   +4 more
core   +4 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Screening Performance Characteristic of Ultrasonography and Radiography in Detection of Pleural Effusion; a Meta-Analysis

Emergency, 2016
Introduction: The role of ultrasonography in detection of pleural effusion has long been a subject of interest but controversial results have been reported.
Mahmoud Yousefifard, Masoud Baikpour, Parisa Ghelichkhani, Hadi Asady, Kavous Shahsavari Nia, Ali Moghadas Jafari, Mostafa Hosseini, Saeed Safari   +7 more
doaj  

Preoperative laboratory evaluation of patients aged over 40 years undergoing elective non-cardiac surgery

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Although it is generally agreed that a medical history and physical examination should be obtained as part of preoperative evaluation, there is still substantial controversy about the additional benefits of preoperative screening ...
Fábio Yoshito Ajimura, Alex Silva Santos Freire Maia, Adriana Hachiya, Alexandra Sayuri Watanabe, Maria do Patrocínio Tenório Nunes, Mílton de Arruda Martins, Fábio Santana Machado   +6 more
doaj   +1 more source