Results 61 to 70 of about 324,544 (261)

Performance of Xpert MTB/RIF and acid-fast bacilli smear microscopy for the diagnosis of pulmonary tuberculosis using bronchoalveolar lavage samples in negative or sputum-scarce adults in Colombia: a retrospective diagnostic accuracy study

BMC Infectious Diseases
Background Limited literature exists on the diagnostic yield of traditional and molecular tuberculosis (TB) tests using bronchoalveolar lavage (BAL) specimens in high burden South American countries. The aim of the study is to determine the value of acid-
Vanessa Sabella-Jiménez, Valentina L. Sabella-Jiménez, Valentina Restrepo-Espinosa, Juanita Eljadue-Flórez, Claredit Valentina Gallardo-Castro, Andrea Alexandra Silvera, Carlos Otero-Herrera, Hugo Andrés Macareno Arroyo, Jorge Acosta-Reyes, Jorge Luis Quintero Barrios   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Diagnostic Significance of Eye Tracking Tests, Optokinetic Nystagmus Tests, and Visual Suppression Tests on Routine ENG Tests.

Equilibrium Research, 2000
In order to clarify the diagnostic significance of eye tracking tests (ETT), optokinetic nystagmus tests (OKN), and visual suppression test (VST) on routine ENG tests, we investigated the findings of ETT, OKN, and VST in 1, 225 patients who complained of vertigo and dizziness, and in 440 of the patients, we compared these findings with MRI ...
Tadashi Nakamura, Takashi Nasu, Shin Yoshida, Shuji Koike, Teruaki Nagase, Yumiko Takano, Yasukazu Hozumi, Masaru Aoyagi   +7 more
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Melting the eis: Nondetection of Kanamycin Resistance Markers by Routine Diagnostic Tests and Identification of New eis Promoter Variants. [PDF]

Antimicrob Agents Chemother, 2021
Ley SD, Pillay S, Streicher EM, van der Heijden YF, Sirgel F, Derendinger B, de Kock M, Gagneux S, Warren RM, Theron G, de Vos M.   +10 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Screening Performance Characteristic of Ultrasonography and Radiography in Detection of Pleural Effusion; a Meta-Analysis

Emergency, 2016
Introduction: The role of ultrasonography in detection of pleural effusion has long been a subject of interest but controversial results have been reported.
Mahmoud Yousefifard, Masoud Baikpour, Parisa Ghelichkhani, Hadi Asady, Kavous Shahsavari Nia, Ali Moghadas Jafari, Mostafa Hosseini, Saeed Safari   +7 more
doaj  

Frequency and indication of non-musculoskeletal examinations: a cross-sectional survey of Quebec chiropractors

Chiropractic & Manual Therapies
Background Approximately 1% of low back pain is estimated to be caused by serious systemic diseases, including cancer, infection, or abdominal aortic dissection.
Danikel Giroux, Chloé Branconnier, André Bussières, Jean Théroux, Marc-André Blanchette   +4 more
doaj   +1 more source

Preoperative laboratory evaluation of patients aged over 40 years undergoing elective non-cardiac surgery

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Although it is generally agreed that a medical history and physical examination should be obtained as part of preoperative evaluation, there is still substantial controversy about the additional benefits of preoperative screening ...
Fábio Yoshito Ajimura, Alex Silva Santos Freire Maia, Adriana Hachiya, Alexandra Sayuri Watanabe, Maria do Patrocínio Tenório Nunes, Mílton de Arruda Martins, Fábio Santana Machado   +6 more
doaj   +1 more source

Reduced amplification efficiency of the RNA-dependent-RNA-polymerase target enables tracking of the Delta SARS-CoV-2 variant using routine diagnostic tests. [PDF]

J Virol Methods, 2022
Valley-Omar Z, Marais G, Iranzadeh A, Naidoo M, Korsman S, Maponga T, Hussey H, Davies MA, Boulle A, Doolabh D, Laubscher M, Wojno J, Deetlefs JD, Maritz J, Scott L, Msomi N, Naicker C, Tegally H, de Oliveira T, Bhiman J, Williamson C, Preiser W, Hardie D, Hsiao NY.   +23 more
europepmc   +1 more source