Results 51 to 60 of about 44,409 (306)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
In delay-tolerant wireless sensor networks, messages for sensor data are delivered using opportunistic contacts between intermittently connected nodes. Since there is no stable end-to-end routing path like the Internet and mobile nodes operate on battery,
Min Wook Kang, Yun Won Chung
doaj +1 more source
Design of MANET Routing Based on Node Stability and Cross-layer Optimization [PDF]
Aiming at the problem of poor routing stability and high end-to-end delay in the Optimized Link State Routing(OLSR) protocol in Mobile Ad-hoc Network(MANET),an improved OLSR routing protocol is proposed.In view of the mobility characteristic of the MANET
SHEN Weiyang,LIU Qiang,OUYANG Feng
doaj +1 more source
Weight-Based PA-GPSR Protocol Improvement Method in VANET
Vehicle Ad-hoc network (VANET) can provide technical support and solutions for the construction of intelligent and efficient transportation systems, and the routing protocol directly affects the efficiency of VANET. The rapid movement of nodes and uneven
Wenzhu Zhang +3 more
doaj +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Energy-aware peering routing protocol for indoor hospital body area network communication
The recent research in Body Area Networks (BAN) is focused on making its communication more reliable, energy efficient, secure, and to better utilize system resources.
Aslam, Nauman +3 more
core +1 more source
Performance Analysis of DTN Using Level Signal Priority Epidemic Routing Protocol
A DTN architecture consists of several nodes that are connected with high dynamic topology. The routing protocol is an important part which determine the DTN performance system.
Ahmad Zainudin +2 more
doaj +3 more sources
Routing adalah proses pemilihan rute terbaik untuk suatu paket data agar dapat sampai ke tujuannya. Proses routing sangat dibutuhkan dalam proses pengiriman data.
Nur Indah, Yulita Salim, Ramdan Satra
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

