The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
Memorandum of understanding relating to the comprehensive, continuing and cooperative transportation planning process in the Boston Metropolitan Area [PDF]
INTRODUCTION:We undertook a comparative survey of gastric emptying (GE) kinetics after two variants of bypass surgery for upper bowel obstruction. MATERIAL & METHODS:In 10 dogs with experimental upper bowel obstruction, five were randomized to obtain ...
Anna Kasicka-Jonderko +7 more
core +3 more sources
Magnetic compression anastomosis using a double-balloon enteroscope for complete obstruction of Roux-en-Y hepaticojejunostomy anastomosis [PDF]
Dilara Turan Gökçe +2 more
openalex +1 more source
ABSTRACT For individuals living with obesity, bariatric surgery is an effective intervention for type 2 diabetes mellitus (T2DM) remission. Given the established relationships between trauma and obesity, and obesity and T2DM, there is a need to examine bariatric surgical practices from a trauma‐ and violence‐informed care (TVIC) perspective.
Michelle Greenway +7 more
wiley +1 more source
ABSTRACT Background Primary hyperoxaluria type 1 (PH1) is a rare autosomal recessive disorder that leads to systemic oxalosis and end‐stage renal disease (ESRD). Before the advent of siRNA therapy, liver transplantation, often combined with kidney transplantation, was the only definitive treatment.
Gal Finer +5 more
wiley +1 more source
The esophagogastric junctional adenocarcinoma an increasing disease [PDF]
Identifying and defining the esophagogastric junctional adenocarcinoma (EGJA) as an independent disease apart from gastric cancer (GC) and esophagus cancer (EG) it has always been a difficult issue entailing doubts about the appropriate therapeutic ...
Andreetti, Claudio +3 more
core +1 more source
Correction to: Letter to the Editor Outcome of Sleeve Gastrectomy Converted to Roux-en-Y Gastric Bypass and One-Anastomosis Gastric Bypass [PDF]
Mohit Bhatia +2 more
openalex +1 more source
This study investigated the utility of the Japanese NCD risk calculator for preoperative assessment in elderly patients undergoing pancreaticoduodenectomy (PD), using a validation study design. In the training cohort, two preoperative factors—the predicted incidence of postoperative ADL decline ≥ 44.8% and Clavien–Dindo grade IV or higher complications
Nana Kimura +9 more
wiley +1 more source
Comparison of uncut Roux-en-Y anastomosis and traditional Roux-en-Y anastomosis in the totally laparoscopic distal gastrectomy for gastric cancer: An analysis of multiple centers' data [PDF]
目的对比非离断式(Uncut)Roux-en-Y吻合和传统Roux-en-Y吻合应用于全腹腔镜远端胃癌根治术后消化道重建的安全性和短期疗效。方法回顾性分析国内10家单位共60例远端胃癌根治术后全腹腔镜消化道重建的胃癌病人临床资料,根据消化道重建方式不同分为Uncut Roux-en-Y组(Uncut组)34例,传统Roux-enY组(传统组)26例。结果 Uncut Roux-en-Y吻合在消化道重建时间方面用时更短[(51.5±13.3)min vs.(80.4±16.2)min,P=0.000 ...
冯兴宇 +10 more
core
Stapled intestinal anastomosis is a simple and reliable method for management of intestinal caliber discrepancy in children [PDF]
PURPOSE: Popularity of minimally invasive surgeries has led to the development of stapled intestinal anastomosis for adults. The advanced instruments used in this technique are getting suitable with the small intestinal lumens of neonates and infants. We
Hiroo Uchida +5 more
core +1 more source

