Advanced Science, EarlyView.DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng +16 more
wiley +1 more source
Thermal performance curves and age-stage, two-sex life table of <i>Dermatophagoides farinae</i> (Acari: Pyroglyphidae): baseline data for climate change impact assessment. [PDF]
Front Insect SciXu Z +5 more
europepmc +1 more source
Advanced Science, EarlyView.FAK orchestrates a mechanical barrier limiting nanomedicine accumulation in solid tumors by coupling ECM remodeling with cytoskeletal tension. Genetic or pharmacological FAK inhibition dismantles this barrier, enhances clathrin‐mediated uptake and penetration, and overcomes delivery limitations to improve antitumor efficacy.
Tian Zhao +11 more
wiley +1 more source
Active-controlled commercial field evaluation of an independently developed fluralaner oral solution for poultry red mite control in laying hens. [PDF]
Poult SciLiu Z +8 more
europepmc +1 more source
Nanoscale Buried Interface Control in Silicone Hydrogels Enables a Biointerface Engineering Platform
Advanced Science, EarlyView.A hydrophilic coating with controllable nanoscale thickness is applied to commercial silicone hydrogel contact lenses. By combining comprehensive multi‐modal three‐dimensional characterization with an advanced algorithm, the thickness and chemical information of these multilayered structures are resolved.
Po‐Hsiang Chen +5 more
wiley +1 more source
Standardized In-house Protocol for Determining the Minimum Inhibitory Concentration (MIC) via Broth Microdilution for Natural Products Against Obligate Anaerobic Bacteria. [PDF]
Curr ProtocGonçalves DS +3 more
europepmc +1 more source
'CERNEY HOUSE. The Seat of William Croome, Esq. To whom this plate is respectfully inscribed by J & H. S. Storer. Published June 1, 1825, by Sherwood, Jones & Co. Paternoster Row.
core
Advanced Science, EarlyView.By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Association between dentists' awareness of antimicrobial resistance and selection of oral third-generation cephalosporins: a cross-sectional study. [PDF]
Antimicrob Steward Healthc EpidemiolTai T +7 more
europepmc +1 more source