Results 31 to 40 of about 4,189,019 (301)
npj Parkinson's Disease, 2023 Terazosin is an α1-adrenergic receptor antagonist that enhances glycolysis and increases cellular ATP by binding to the enzyme phosphoglycerate kinase 1 (PGK1). Recent work has shown that terazosin is protective against motor dysfunction in rodent models
Matthew A. Weber +7 more
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Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
Nature Communications, 2017 Polyamines bind to nucleic acids and their function is regulated by reversible acetylation. Here, the authors show that histone deacetylase 10 is a polyamine deacetylase and present its crystal structure with a bound polyamine transition state analogue ...
Yang Hai +3 more
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Mobility and Insurgent Celebrityhood: The Case of Arundhati Roy
Open Cultural Studies, 2017 Indian novelist and Booker winner Arundhati Roy is a celebrity author, but her celebrityhood is a cross-genre and cross-domain one. This essay argues that a certain insurgent celebrityhood emerges in the case of Roy through her mobility into and across ...
Nayar Pramod K.
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Trajectoires, 2020 Le passage d’un pouvoir temporel séparé du pouvoir spirituel à une forme protestante de double pouvoir avec la sacralité du prince chef de son Église semble s’être fait dans l’urgence du contexte de la rupture de Luther avec la papauté romaine. L’article examine en détail comment cette nouvelle combinaison des deux pouvoirs trouve ses racines dans la ...
openaire +3 more sources
Proyección, 2021 Hace 100 años, en 1921, se conocieron Pierre Teilhard de Chardin y Édouard Le Roy. De la amistad entre ellos sabemos mucho por la correspondencia que se extendíó durante 25 años, desde 1921 a 1946.
Leandro Sequeiros San Román
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Scientific ReportsAyurveda, a traditional Indian system of medicine, advocates the use of processed Plumbago zeylanica L. roots for managing inflammatory and rheumatic conditions. However, scientific evidence supporting its anti-arthritic potential remains unexplored. Our
Tanmoy Das +5 more
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CHARACTERIZATION OF UNIVARIATE LONG-TERM URBAN INTERNET TRAFFIC VOLUME
ICTACT Journal on Communication Technology, 2017 The proposed work deals with a real time hourly internet traffic data set in bits collected from ISPs located in 11 cities of European Country for the period 7th June 2005 to 31st July 2005.
Subhasish Debroy +4 more
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CAAI Transactions on Intelligence Technology, 2022 The convenience of availing quality services at affordable costs anytime and anywhere makes mobile technology very popular among users. Due to this popularity, there has been a huge rise in mobile data volume, applications, types of services, and number ...
Raj Kumar Samanta +5 more
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source