Results 31 to 40 of about 709,785 (279)

Polymorph Selection of ROY by Flow-Driven Crystallization

Crystals, 2019
The selection of polymorphs of the organic compound 5-methyl-2-[(2-nitrophenyl)amino]-3-thiophenecarbonitrile, ROY, is studied experimentally in the confined space between two horizontal glass plates when an acetone solution of ROY of variable ...
Iwona Ziemecka, Sindy Gokalp, Sander Stroobants, Fabian Brau, Dominique Maes, Anne De Wit   +5 more
doaj   +1 more source

Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

Nature Communications, 2017
Polyamines bind to nucleic acids and their function is regulated by reversible acetylation. Here, the authors show that histone deacetylase 10 is a polyamine deacetylase and present its crystal structure with a bound polyamine transition state analogue ...
Yang Hai, Stephen A. Shinsky, Nicholas J. Porter, David W. Christianson   +3 more
doaj   +1 more source

CHARACTERIZATION OF UNIVARIATE LONG-TERM URBAN INTERNET TRAFFIC VOLUME

ICTACT Journal on Communication Technology, 2017
The proposed work deals with a real time hourly internet traffic data set in bits collected from ISPs located in 11 cities of European Country for the period 7th June 2005 to 31st July 2005.
Subhasish Debroy, Rajdeep Ray, Mofazzal Hossain Khondekar, Baisakhi Chakraborty, Anup Kumar Bhattacharjee   +4 more
doaj   +1 more source

Scope of machine learning applications for addressing the challenges in next‐generation wireless networks

CAAI Transactions on Intelligence Technology, 2022
The convenience of availing quality services at affordable costs anytime and anywhere makes mobile technology very popular among users. Due to this popularity, there has been a huge rise in mobile data volume, applications, types of services, and number ...
Raj Kumar Samanta, Bikash Sadhukhan, Hiranmay Samaddar, Suvobrata Sarkar, Chandan Koner, Monidepa Ghosh   +5 more
doaj   +1 more source

Du roi-prêtre au roi

Trajectoires, 2020
Le passage d’un pouvoir temporel séparé du pouvoir spirituel à une forme protestante de double pouvoir avec la sacralité du prince chef de son Église semble s’être fait dans l’urgence du contexte de la rupture de Luther avec la papauté romaine. L’article examine en détail comment cette nouvelle combinaison des deux pouvoirs trouve ses racines dans la ...
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Preclinical assessment of anti-arthritic activity of methanolic extract from processed Plumbago zeylanica roots

Scientific Reports
Ayurveda, a traditional Indian system of medicine, advocates the use of processed Plumbago zeylanica L. roots for managing inflammatory and rheumatic conditions. However, scientific evidence supporting its anti-arthritic potential remains unexplored. Our
Tanmoy Das, Yadu Nandan Dey, Tamal Pal, Payel Ghosh, Atreyee Ganguly, Suman Mondal   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Extraction optimization and reactivity of 7α-acetoxy-6β-hydroxyroyleanone and ability of its derivatives to modulate PKC isoforms

Scientific Reports
Protein kinase C is a family of kinases that play important roles in carcinogenesis. Medicinal plants from Plectranthus spp. (Lamiaceae) are a well-known source of interesting abietanes, such as 7α-acetoxy-6β-hydroxyroyleanone (Roy).
Vera M. S. Isca, Gabrielle Bangay, Salvatore Princiotto, Lucília Saraíva, Daniel J. V. A. dos Santos, Alfonso T. García-Sosa, Patrícia Rijo   +6 more
doaj   +1 more source

Les archives sans repos: enjeux d’une édition électronique

Digital Studies, 2019
In 1970, Gabrielle Roy published Windflower (La Rivière sans repos), a short novel preceded by three short stories “Nouvelles Esquimaudes.” Conserved in the Gabrielle Roy collection of Library and Archives Canada, the archives contain a myriad of ...
Jacinthe Martel, Nathanaël Pono
doaj   +2 more sources