Results 221 to 230 of about 2,151,276 (283)

Mechanistic trials, therapy and developmental science—An exemplar from early autism care

open access: yesJCPP Advances, EarlyView.
Abstract Background Mechanistic design and analysis in clinical trials remains relatively rare in child mental health and autism, despite the considerable value that it could have in developing therapy practice and in illuminating basic science. Clinical trials themselves continue to have insufficient influence on actual clinical practice in child ...
Jonathan Green
wiley   +1 more source

Loss of Y chromosome in Alzheimer's patients co-occurs with somatic mutations beyond CHIP drivers. [PDF]

open access: yesLife Sci Alliance
Rychlicka-Buniowska E   +19 more
europepmc   +1 more source

Longitudinal associations between play experiences and trajectories of preschoolers' mental health from April–July, 2020

open access: yesJCPP Advances, EarlyView.
Based on data collected monthly from April to July 2020, we found that time spent playing outside and with other children were associated with lower internalising problems across time in preschool‐aged children, whereas more time spent playing alone was associated with more severe internalising problems.
Helen F. Dodd   +3 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Acting authentically: Using play to cultivate authentic interrelating in role performance

open access: yesJournal of Organizational Behavior, EarlyView.
Summary Research is increasingly demonstrating that authenticity and human connection are fundamental and interrelated human needs. However, organizational roles often constrain authenticity and connection in workplace interactions, especially roles that are highly scripted.
Lyndon E. Garrett
wiley   +1 more source

Promoting Fun or Competition? Testing Interventions on Ludic and Agonistic Work Design

open access: yesJournal of Organizational Behavior, EarlyView.
ABSTRACT Research highlights the benefits of play‐at‐work, yet little is known about training employees to self‐initiate it. We tested two programs to train employees on designing work with elements of fun (ludic work design [LWD]) or competition (agonistic work design [AWD]).
Jan E. Walsken   +2 more
wiley   +1 more source

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