Results 221 to 230 of about 639,063 (347)

Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Andexanet alfa was recommended by the National Institute for Health and Clinical Excellence (NICE) as an option in the management of life‐threatening gastrointestinal bleeding in patients taking apixaban or rivaroxaban in May 2021. A recent UK‐wide survey of local hospital protocols for the use of andexanet alfa suggested that practice ...
Louis Fisher   +11 more
wiley   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon   +13 more
wiley   +1 more source

Teacher‐makers and teacher‐breakers: (Re)defining how status and safety influence trajectories into and away from teaching

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper uses empirical data from a longitudinal qualitative study conducted with aspirant teachers in England to propose (re)definitions of the concepts of ‘status’ and ‘safety’ as a framework with which to understand and improve teacher recruitment.
Emily MacLeod
wiley   +1 more source

Correction: THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity. [PDF]

open access: yesChem Sci
Qin L   +12 more
europepmc   +1 more source

Can boarding schools help looked after and vulnerable children improve academic attainment?

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The education of children in statutory care, or at the edge of care, is a serious concern for governments and policymakers. How to promote educational opportunities for these children can involve challenging and often contentious proposals. In this paper, we study one proposal put into practice in England: the provision to children who are in ...
David Murphy   +2 more
wiley   +1 more source

Patient and Public Involvement and Engagement (PPIE) In Neurosurgery

open access: yesBrain and Spine
Mr Duranka Perera   +6 more
doaj   +1 more source

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