Results 41 to 50 of about 1,424,236 (352)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Les lettres de voiture dans les ouvrages de l’ancien droit français (xviie - xviiie siècle)

Clio@Themis, 2019
In the 17th and 18th centuries, consignment notes are acts that describe the terms of the contract for carriage of goods. They can be used by the parties as evidence and are used by the royal power to control the carriage of goods.
Céline Drand
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Design Aspects and Performance Evaluation of Pole-Phase Changing Induction Machines

Energies, 2022
Pole-phase changing induction machines (IMs) offer the capability to extend the torque-speed envelope compared to their fixed pole-phase counterparts. Dynamic pole-changing can achieve higher torque levels at lower speeds, utilizing higher pole numbers ...
Konstantina Bitsi, Sjoerd G. Bosga, Oskar Wallmark   +2 more
doaj   +1 more source

Power distribution investigation of a hexagonal diffused cellular indoor visible light communications system [PDF]

, 2011
This paper presents a three dimensions (3D) model of optical power distribution in a diffused cellular indoor visible light communication (VLC) system.
Ghassemlooy, Zabih, Le Minh, Hoa, Rajbhandari, Sujan, Wu, Dehao   +3 more
core  

Deep XMM Observations of Draco rule out at the 99% Confidence Level a Dark Matter Decay Origin for the 3.5 keV Line [PDF]

, 2016
We searched for an X-ray line at energies around 3.5 keV in deep, ~1.6 Msec XMM-Newton observations of the dwarf spheroidal galaxy Draco. No line was found in either the MOS or the PN detectors.
Jeltema, Tesla E., Profumo, Stefano
core   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Trouver le chemin de la grâce : les villes rebelles et leurs stratégies pour rétablir le dialogue avec le souverain (royaume de France, seconde moitié du XVe siècle)

Criminocorpus
Repression of urban uprisings in the second half of the 15th century gave rise to negotiations between the king and the city. However, the search for agreement is rarely mentioned in the documentation.
Adrien Carbonnet
doaj   +1 more source

LINGUAL SEMIOTICS OF ABSOLUTE POWER IN THE TUDORS’ TIMES

Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2017
The paper addresses the phenomenon of absolute power enablement in Great Britain of the 15th-16th centuries from the perspective of social semiotics and semantics: it includes the definition of obligatory and optional parameters of power and ...
Tatyana N. Astafurova, Andrey V. Olyanich   +1 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source