NMR‐Guided Fragment Screening Identifies Privileged Noncanonical Amino Acids for mRNA Display
A strategy is reported to prescreen and prioritize noncanonical amino acids as fragments prior to their use in mRNA display peptide libraries. Using MDM2 as a target, two ncAAs that bind to the Trp binding pocket in MDM2 are found by protein‐observed NMR.
Abdul J. Castillo +8 more
wiley +1 more source
Structural characterization of ribosome recycling and fusidic acid inhibition in Staphylococcus aureus. [PDF]
González-López A, Selmer M.
europepmc +1 more source
Electrically evoked compound action potentials in adult and pediatric cochlear implant users: I. Cochlear nerve responsiveness and electrode-neuron interface index. [PDF]
Gao Z, Oleson JJ, Gifford RH, He S.
europepmc +1 more source
Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans
RNA interference (RNAi) is widely used in life science research and is critical for diverse biological processes, such as germline development and antiviral defense.
Katsufumi Dejima +2 more
core +1 more source
Prenatal Diagnosis, Volume 46, Issue 11, Page 1683-1702, October 2026.
Zandra C. Deans +18 more
wiley +1 more source
Development of Robust Ratio Linear Fitting Method of Temperature and Emissivity Separation for High-Temperature Data. [PDF]
Manzardo M +4 more
europepmc +1 more source
Protein-RNA interplay in translation. Structural studies of RRF, SelB and L1.
Translation is a central biological process, that is catalysed by a machinery consisting of RNA and protein. In this thesis three different protein components of the bacterial protein synthesis system have been structurally studied.
Selmer, Maria
core
A TCER-1-siRNA regulatory axis suppresses antibacterial innate immunity in C. elegans. [PDF]
Naim N +9 more
europepmc +1 more source
Location and mapping of the human rostromedial tegmental nucleus and associated midbrain inhibitory nuclei regulating dopamine neurons. [PDF]
Filimontseva A, Fu Y, Halliday GM.
europepmc +1 more source
Sultams as Dual Inhibitors of Human Carbonic Anhydrase and Thioredoxin Reductase. [PDF]
Pustenko A +8 more
europepmc +1 more source

