Results 221 to 230 of about 675,402 (336)

ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metastasis by Regulating the PALLD‐Mediated EMT Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding   +16 more
wiley   +1 more source

AmrProfiler: a comprehensive tool for identifying antimicrobial resistance genes and mutations across species. [PDF]

open access: yesNucleic Acids Res
Skoulakis A   +5 more
europepmc   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang   +28 more
wiley   +1 more source

Perspectives of RNAi, CUADb and CRISPR/Cas as Innovative Antisense Technologies for Insect Pest Control: From Discovery to Practice. [PDF]

open access: yesInsects
Kumar H   +8 more
europepmc   +1 more source

The Ribonucleotide Sequence of 5S rRNA from Two Strains of Deep-Sea Barophilic Bacteria

open access: bronze, 1984
Jody W. Deming   +4 more
openalex   +1 more source

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