Results 221 to 230 of about 696,870 (312)

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Can geometric combinatorics improve RNA branching predictions? [PDF]

BMC Bioinformatics
Poznanović S, Cardwell O, Heitsch C.
europepmc   +1 more source

GyrB <i>vs.</i> 16s rRna sequencing for the identification of <i>Campylobacter jejuni</i>, <i>Campylobacter coli</i>, and <i>Campylobacter lari</i>

, 2011
Nereus W. Gunther, Jonnee Almond, Xianghe Yan, David S. Needleman   +3 more
openalex   +1 more source

Phylogenetic analysis of Bacteroidales 16S rRNA gene sequences from human and animal effluents and assessment of ruminant faecal pollution by real‐time PCR [PDF]

, 2009
Sophie Mieszkin, Jean Fabrice Yala, Rozenn Joubrel, Michèle Gourmelon   +3 more
openalex   +1 more source

Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor Progression

Advanced Science, EarlyView.
Cancer cells drive adjacent adipose tissue to release fatty acids by secreting CCL2, which activates PPARα‐dependent lipolysis. The resulting fatty acid influx amplifies HIF‐1α/CCL2 signaling, establishing a positive feedback loop that fuels tumor growth.
Jeong‐Eun Yun, Jieun Seo, Jiwon Koh, Seock‐Ah Im, Ki Yong Hong, Yeseon Son, Do‐Won Jeong, Junji Fukuda, Jong‐Wan Park, Yang‐Sook Chun   +9 more
wiley   +1 more source

Molecular prevalence of Chlamydia spp. in wild birds from Qinghai Lake, China. [PDF]

Ir Vet J
Wu X, Lei F, Niu Y, Yu J, Chen C, Ba T, Liang L.   +6 more
europepmc   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, EarlyView.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Plastid RNA Editing in <i>Glycyrrhiza uralensis</i>: Landscape Characterization and Comparative Assessment of RNA-Seq Library Strategies for Detection. [PDF]

Genes (Basel)
Ma H, Rao Y, Lu Y, Fang N, Huang Y, Gong L.   +5 more
europepmc   +1 more source

Can Targeting Non-Contiguous V-Regions With Paired-End Sequencing Improve 16S rRNA-Based Taxonomic Resolution of Microbiomes?: An In Silico Evaluation

, 2019
Nishal Kumar Pinna, Anirban Dutta, Mohammed Monzoorul Haque, Sharmila S. Mande   +3 more
openalex   +1 more source

Lactobacillus Salivarius‐Derived Indole‐3‐Acetic Acid Promotes AHR‐PARP1 Axis‐Mediated DNA Repair to Mitigate Intestinal Aging

Advanced Science, EarlyView.
Indole‐3‐acetic acid (IAA) acting as one of the aryl hydrocarbon receptor (AHR) endogenous ligands is identified to be derived from Lactobacillus salivarius via its catalytic enzyme (ALDH) rather than host cells. Lactobacillus salivarius and IAA supplementation effectively mitigate intestinal aging by facilitating AHR‐poly (ADP‐ribose) polymerase 1 ...
Zheng Cao, Cui Zhang, Hehua Lei, Weichuan Lin, Wenkai Yu, Xin Gao, Yanmeng He, Xinzhi Li, Qingwei Xiang, Zhiwen Zhang, Weifei Luo, Andrew D. Patterson, Limin Zhang, Gang Chen   +13 more
wiley   +1 more source