Results 261 to 270 of about 152,172 (364)

Evaluating the Potential Adverse Effects of Favipiravir on Biochemical, Histopathological, and Spermatological Parameters in Male Rats' Testicular Tissue

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür   +6 more
wiley   +1 more source

Genetic and Inflammatory Signatures Associated With Worse Prognosis in Hospitalized Patients With Severe SARS‐CoV‐2 Infection With and Without Diabetes

open access: yesJournal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SAR‐CoV‐2) presents with a diverse symptomology, ranging from asymptomatic to severe disease, but the mechanism of risk factors such as diabetes remains unelucidated. The current retrospective cohort study of 182 patients, with and without COVID‐19 and diabetes, analyzed leftover blood specimens
Marshall Yuan   +8 more
wiley   +1 more source

Single-cell profiling demonstrates the combined effect of wheeze phenotype and infant viral infection on airway epithelial development. [PDF]

open access: yesSci Adv
Berdnikovs S   +12 more
europepmc   +1 more source

Resveratrol improves TNF-α-induced endothelial dysfunction in a coculture model of a Caco-2 with an endothelial cell line [PDF]

open access: yes, 2016
Toaldo, Isabela Maia   +8 more
core   +2 more sources

IL‐37 Mitigates the Inflammatory Response in Macrophages Induced by SARS‐CoV‐2 Omicron Infection Through the NF‐κB Signaling Pathway

open access: yesMedComm, Volume 6, Issue 6, June 2025.
IL‐37 mitigates the infiltration of macrophages and suppresses the production of macrophage‐associated chemokines (such as CCL3 and CCL4) induced by SARS‐CoV‐2 Omicron infection through NF‐κB signaling pathway. ABSTRACT The expression levels of macrophage‐associated cytokines are significantly greater in COVID‐19 patients than in healthy individuals ...
Feifei Qi   +11 more
wiley   +1 more source

Estimated impact of nirsevimab prophylaxis on the economic burden of respiratory syncytial virus disease in Northern Italy. [PDF]

open access: yesItal J Pediatr
Tzialla C   +7 more
europepmc   +1 more source

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