Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu +12 more
wiley +1 more source
Quantitative Real-Time RT-PCR Verifying Gene Expression Profile of Cavitations Within Human Jaw Bone. [PDF]
Ghanaati S +3 more
europepmc +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
Single-cell RT-PCR Analysis and CRF Effects on TRPC Channels Expressed in Rat Brain
Nicole M. Jones
openalex
Enhancing RT-PCR Throughput and Sensitivity through Large-Scale Sample Pooling Using a Nano-Hybrid Membrane. [PDF]
Lee NE +7 more
europepmc +1 more source
A Novel Multi-Gene Combined RT-PCR Assay for Rapid and Sensitive Detection of Maize Dwarf Mosaic Virus. [PDF]
Jin Y +7 more
europepmc +1 more source
Laboratory-based molecular test alternatives to RT-PCR for the diagnosis of SARS-CoV-2 infection. [PDF]
Arevalo-Rodriguez I +15 more
europepmc +1 more source
Diagnosis of Community-Acquired Pneumonia Due to Influenza or Respiratory Syncytial Virus: Evaluation of RT-PCR Sensitivity in Nasopharyngeal, Saliva, and Sputum Samples. [PDF]
Ramirez J +6 more
europepmc +1 more source
SARS-CoV-2 Variants May Affect Saliva RT-PCR Assay Sensitivity. [PDF]
Chwa JS +10 more
europepmc +1 more source

