Results 11 to 20 of about 867,602 (167)
Understanding heat stress physiology and identifying reliable biomarkers are paramount for developing effective management and mitigation strategies. However, little is known about the molecular mechanisms underlying thermal tolerance in animals.
Jinhuan Dou+6 more
doaj +2 more sources
Discovery and Characterization of Unusual O-Linked Glycosylation of IgG4 Antibody Using LC-MS. [PDF]
ABSTRACT Background Consensus is that immunoglobulin IgG4 contains only N‐linked glycosylation. The analysis of several batches of commercial biopharmaceutical product Dupixent using top‐down intact mass spectrometry revealed that this IgG4 features a small amount of O‐linked glycosylation in the Fab region.
Janecki DJ, Kao-Scharf CY, Hoffmann A.
europepmc +2 more sources
Progress in experimental models to investigate the in vivo and in vitro antidiabetic activity of drugs. [PDF]
Abstract Diabetes mellitus is one of the world's most prevalent and complex metabolic disorders, and it is a rapidly growing global public health issue. It is characterized by hyperglycemia, a condition involving a high blood glucose level brought on by deficiencies in insulin secretion, decreased activity of insulin, or both.
Janapati YK, Junapudi S.
europepmc +2 more sources
BackgroundMyocardial ischemia/reperfusion (I/R) injury is the main obstacle to percutaneous coronary intervention, lacking effective therapeutic measures in a clinical setting.
Xiaohong Wei+9 more
doaj +1 more source
Determinação voltamétrica da capacidade de complexação de águas das sub-bacias do rio Turvo Sujo e do ribeirão São Bartolomeu na Zona da Mata Mineira [PDF]
Humic substances are formed through the decomposition of plants and animal tissues producing complex chemical structures. They are the main organic components of the environment, presenting the ability to complex heavy metals present in natural waters ...
Custódio, Gislene+4 more
core +2 more sources
Optimalisasi Pendokumentasian Case Manager Rumah Sakit Tipe A Di Jakarta
Case management di Indonesia dikenal dengan Manajemen Pelayanan Pasien (MnPP) dan case manager disebut dengan Manajer Pelayanan Pasien (MPP). Fungsi case manager yaitu melakukan asesmen, perencanaan hingga evaluasi, koordinasi, advokasi, edukasi, serta ...
Yandih Mardean+3 more
doaj +1 more source
Genetic Characteristics of the Even Breed of Deer in Yakutia
Microsatellite markers Rt6, BMS1788, Rt 30, Rt1, Rt9, FCB193, Rt7, BMS745, C 143, Rt24, OheQ, C217, C32, NVHRT16, T40, C276 were used to study the genetic profile of the Even breed of deer cultivated in Yakutia.
V. Dodokhov+3 more
semanticscholar +1 more source
1 kW, 10 mJ, 120 fs coherently combined fiber CPA laser system. [PDF]
An ultrafast fiber chirped-pulse amplification laser system based on a coherent combination of 16 ytterbium-doped rod-type amplifiers is presented. It generates 10 mJ pulse energy at 1 kW average power and 120 fs pulse duration.
H. Stark+4 more
semanticscholar +1 more source
Contextual barriers of respectful workplace in nursing: A focused ethnography
Background: Respectful relationship among nurses is an important influencing factor of positive work environment and nursing outcomes. Disrespectful interpersonal behaviors set the scene for an unpleasant and unhealthy workplace in nursing.
Azadeh Nouri+3 more
doaj +1 more source
RESISTANCE TRANING PROTOCOLS PROMOTE STRENGTH INCREASE WITHOUT MORPHOLOGICAL CHANGES
Introduction Resistance training (RT) has been related to increased protein synthesis, and in the myocardium it triggers morphological adaptations that result in improved cardiac contractility. In skeletal muscle, RT promotes an improvement in functional
A. Damiani+8 more
semanticscholar +1 more source