Results 11 to 20 of about 1,054,515 (168)

Comprehensive RNA-Seq Profiling Reveals Temporal and Tissue-Specific Changes in Gene Expression in Sprague–Dawley Rats as Response to Heat Stress Challenges

Frontiers in Genetics, 2021
Understanding heat stress physiology and identifying reliable biomarkers are paramount for developing effective management and mitigation strategies. However, little is known about the molecular mechanisms underlying thermal tolerance in animals.
Jinhuan Dou, Jinhuan Dou, Angela Cánovas, Luiz F. Brito, Ying Yu, Flavio S. Schenkel, Yachun Wang   +6 more
doaj   +2 more sources

Inhalability and Bioactivity of Spray-Dried versus Pressurized Gas eXpanded Liquid Technology-Processed Yeast Beta-Glucan Microparticles for Anti-Fibrotic Therapies. [PDF]

Adv Healthc Mater
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Dowdall N, Naiel S, Zhou Q, Ali P, Yousof TR, Wong E, Couto R, Yépez B, Seifried B, Moquin P, Rhem R, Dolovich M, Kolb MR, Ask K, Hoare T.   +14 more
europepmc   +2 more sources

Proteomics Revealed That Mitochondrial Function Contributed to the Protective Effect of Herba Siegesbeckiae Against Cardiac Ischemia/Reperfusion Injury

Frontiers in Cardiovascular Medicine, 2022
BackgroundMyocardial ischemia/reperfusion (I/R) injury is the main obstacle to percutaneous coronary intervention, lacking effective therapeutic measures in a clinical setting.
Xiaohong Wei, Xiaohong Wei, Yuzhuo Wu, Haie Pan, Qian Zhang, Ke He, Guiyang Xia, Huan Xia, Sheng Lin, Hong-Cai Shang   +9 more
doaj   +1 more source

Determinação voltamétrica da capacidade de complexação de águas das sub-bacias do rio Turvo Sujo e do ribeirão São Bartolomeu na Zona da Mata Mineira [PDF]

, 2021
Humic substances are formed through the decomposition of plants and animal tissues producing complex chemical structures. They are the main organic components of the environment, presenting the ability to complex heavy metals present in natural waters ...
Custódio, Gislene, Damasceno, Odilaine Inácio de Carvalho, Dutra, Rita Aparecida, Reis, César, Reis, Efraim Lázaro   +4 more
core   +2 more sources

Genetic Characteristics of the Even Breed of Deer in Yakutia

, 2021
Microsatellite markers Rt6, BMS1788, Rt 30, Rt1, Rt9, FCB193, Rt7, BMS745, C 143, Rt24, OheQ, C217, C32, NVHRT16, T40, C276 were used to study the genetic profile of the Even breed of deer cultivated in Yakutia.
V. Dodokhov, N. Pavlova, T. Rumyantseva, L. A. Kalashnikov   +3 more
semanticscholar   +1 more source

RESISTANCE TRANING PROTOCOLS PROMOTE STRENGTH INCREASE WITHOUT MORPHOLOGICAL CHANGES

Revista Brasileira de Medicina do Esporte, 2020
Introduction Resistance training (RT) has been related to increased protein synthesis, and in the myocardium it triggers morphological adaptations that result in improved cardiac contractility. In skeletal muscle, RT promotes an improvement in functional
A. Damiani, L. C. Caldas, A. B. Melo, C. Contreiro, Wagner Muller Estevam, B. Nogueira, L. G. Ferreira, A. Leopoldo, Ana Paula Lima Leopoldo   +8 more
semanticscholar   +1 more source

Entrenamiento intermitente de alta intensidad versus continuo en mujeres con hipertensión

Avances en Enfermería, 2020
Objetivo: comparar los efectos de la implementación de un programa de ejercicio continuo de mediana intensidad vs. un programa de ejercicio interválico de alta intensidad sobre los parámetros antropométricos y de condición física en mujeres hipertensas.
Andrés- Felipe Villaquiran-Hurtado, Sandra Jimena Jácome Velasco, Luz Andrea Chantre-Ortega, Leidy Johana Mueses- Tapue, Omar Andrés Ramos-Valencia, Carlos Iván Salazar-Villamarin   +5 more
doaj   +1 more source

Dissecting clonal hematopoiesis in the myeloid compartment of chronic lymphocytic leukemia and Richter transformation. [PDF]

Hemasphere
Abstract The clinical and biological significance of clonal hematopoiesis (CH) has not been investigated in the myeloid compartment of chronic lymphocytic leukemia (CLL). By studying 488 newly diagnosed CLL through CAPP‐seq using a 28‐gene panel on granulocyte genomic DNA (gDNA), CH occurred in 231 (47.3%) patients.
Cosentino C, Mouhssine S, Zucchetto A, Romano I, Salehi M, Cappelli LV, Iannelli F, Almasri M, Maher N, Fumagalli L, Cardinali D, Visentin A, Nabki J, Cividini L, Al Deeban B, Lazzaro M, Maiellaro F, Gaglio A, Perutelli F, Griggio V, Dondolin R, Bellia M, Nicolosi M, Rasi S, Secomandi E, Caneparo V, Mahmoud AM, Deambrogi C, Kogila S, Ghanej J, Nawabi MR, Del Giudice I, Albi E, Vitale C, Scarfò L, Coscia M, Trentin L, Pileri S, Ghia P, Chiarle R, Gattei V, Terzi di Bergamo L, Rossi D, Foà R, Gaidano G, Moia R.   +45 more
europepmc   +2 more sources

Tislelizumab plus zanubrutinib for Richter transformation: the phase 2 RT1 trial

Nature Medicine, 2023
In a large single-arm phase 2 trial, the anti-PD-1 inhibitor tislelizumab combined with the next-generation BTK inhibitor zanubrutinib had an overall response rate of 58.3% and was well tolerated in patients with Richter’s transformation.
O. Al-Sawaf, R. Ligtvoet, S. Robrecht, Janina Stumpf, A. Fink, E. Tausch, C. Schneider, S. Boettcher, Martin Mikusko, M. Ritgen, J. Schetelig, J. von Tresckow, U. Vehling-Kaiser, T. Gaska, C. Wendtner, B. Chapuy, K. Fischer, K. Kreuzer, S. Stilgenbauer, Philipp B. Staber, C. Niemann, Michael Hallek, B. Eichhorst   +22 more
semanticscholar   +1 more source

Aesthetics and Patient-Reported Outcomes in Periodontology and Implant Dentistry: Consensus Report. [PDF]

J Clin Periodontol
ABSTRACT Background Aesthetics and patient‐reported experiences (PREs) and outcomes (PROs) influence treatment choices, but have been largely overlooked in periodontology and implant dentistry. This consensus conference evaluated these factors by focusing on gingival recession defects (GRDs), immediate or early/delayed implant placement and peri ...
Tonetti M, Sanz M, Cairo F, Nart J, Chapple I, Aimetti M, Aroca S, Avila-Ortiz G, Blanco J, Bujaldón A, Cavalcanti R, Cortellini P, Cosyn J, Danser M, de Sanctis M, Derks J, Dommisch H, Figuero E, Gianserra R, Graziani F, Jepsen S, Kebschull M, Lambert F, Montero E, Naenni N, Needleman I, Pilloni A, Ramanauskaite A, Roccuzzo M, Sanz-Martín I, Sanz-Sánchez I, Schwarz F, Sculean A, Stefanini M, Thoma D, Trombelli L, Valles C, West N, Zucchelli G, Zuhr O, Herrera D.   +40 more
europepmc   +2 more sources