Results 21 to 30 of about 867,602 (167)

Tislelizumab plus zanubrutinib for Richter transformation: the phase 2 RT1 trial

open access: yesNature Network Boston, 2023
In a large single-arm phase 2 trial, the anti-PD-1 inhibitor tislelizumab combined with the next-generation BTK inhibitor zanubrutinib had an overall response rate of 58.3% and was well tolerated in patients with Richter’s transformation.
O. Al-Sawaf   +22 more
semanticscholar   +1 more source

Strategies to improve BCG-mediated protection from Mycobacterium tuberculosis [PDF]

open access: yes, 2004
Background: Host resistance to pulmonary tuberculosis is associated with the induction of IFN-y secreting T cells in the lung. Recombinant viruses used in heterologous prime-boost immunisation regimens can evoke powerful T cell immune responses and are ...
Goonetilleke, Nilu
core   +1 more source

Psychological Resilience of Second-Pregnancy Women in China: A Cross-sectional Study of Influencing Factors

open access: yesAsian Nursing Research, 2021
Purpose: The aim of the study was to evaluate the status of psychological resilience among women in their second pregnancy and to investigate the possible influencing factors.
Xiaohuan Jin   +6 more
doaj  

THE ROLE OF REHABILITATION NURSES TO THE ARCHITECTURAL ACCESSIBILITY PROMOTION

open access: yesRevista Portuguesa de Enfermagem de Reabilitação, 2018
Background: the rehabilitation nurses are decisive to the promotion of accessibility trough architectural barriers elimination, which promotes the reintegration of people with reduced mobility.
Rute Salomé da Silva Pereira   +4 more
doaj   +1 more source

Analysis of functional renal allograft tolerance with single-dose rapamycin based induction immunosuppression.

open access: yesTransplantation, 1997
The induction of transplantation tolerance is one of the primary goals following solid organ transplantation. The combination of a single dose of rapamycin (RAPA) with a short course of cyclosporine (CsA) has been shown to induce transplantation ...
W. Goggins   +9 more
semanticscholar   +1 more source

The Adaptation of the Buddhist Death Acceptance Scale for Vietnamese Persons with Cancer

open access: yesAsian Nursing Research, 2021
Purpose: This study reports on selected psychometric properties of the adapted Buddhist Death Acceptance Scale (BDAS) for Vietnamese persons with cancer.
Nguyen H. Long, Sureeporn Thanasilp
doaj  

Chronic rejection: insights from a novel immunosuppressive-free model of kidney transplantation.

open access: yesJournal of the American Society of Nephrology, 2004
The use of immunosuppressive drugs in models of chronic rejection may limit their usefulness for mechanistic studies. We have developed a new minor histocompatibility-mismatched rat kidney transplant model without the need for immunosuppression.
M. Gasser   +6 more
semanticscholar   +1 more source

Changes in drought features at the European level over the last 120 years

open access: yesNatural Hazards and Earth System Sciences, 2021
. In this study we analyze drought features at the European level over the period 1901–2019 using three drought indices: the standardized precipitation index (SPI), the standardized precipitation evapotranspiration index (SPEI), and the self-calibrated ...
M. Ionita, V. Nagavciuc
semanticscholar   +1 more source

THE CLL‐RT1 TRIAL: A MULTICENTER PHASE‐2 TRIAL OF ZANUBRUTINIB, A BTK INHIBITOR, PLUS TISLELIZUMAB, A PD‐1 INHIBITOR, FOR PATIENTS WITH RICHTER TRANSFORMATION

open access: yesHematological Oncology, 2021
than one prior line of RT therapy and allogeneic stem cell transplantation up to 100 days prior to screening. Each treatment cycle (à 21 days) consists of one infusion of 200 mg tislelizumab at day 1 and 160 mg zanubrutinib twice daily orally. Six cycles
O. Al-Sawaf   +17 more
semanticscholar   +1 more source

Plant growth-promoting potential of bacterial isolates from the rhizosphere of Deschampsia antarctica

open access: yesУкраїнський антарктичний журнал
Plants’ adaptations, in combination with the rhizosphere and endosphere microbiome, ensure their survival in the extreme conditions of the Antarctic. The work aimed to quantify the culturable microorganisms of different groups and establish the plant ...
Olga Maslovska   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy