Results 21 to 30 of about 867,602 (167)
Tislelizumab plus zanubrutinib for Richter transformation: the phase 2 RT1 trial
In a large single-arm phase 2 trial, the anti-PD-1 inhibitor tislelizumab combined with the next-generation BTK inhibitor zanubrutinib had an overall response rate of 58.3% and was well tolerated in patients with Richter’s transformation.
O. Al-Sawaf+22 more
semanticscholar +1 more source
Strategies to improve BCG-mediated protection from Mycobacterium tuberculosis [PDF]
Background: Host resistance to pulmonary tuberculosis is associated with the induction of IFN-y secreting T cells in the lung. Recombinant viruses used in heterologous prime-boost immunisation regimens can evoke powerful T cell immune responses and are ...
Goonetilleke, Nilu
core +1 more source
Purpose: The aim of the study was to evaluate the status of psychological resilience among women in their second pregnancy and to investigate the possible influencing factors.
Xiaohuan Jin+6 more
doaj
THE ROLE OF REHABILITATION NURSES TO THE ARCHITECTURAL ACCESSIBILITY PROMOTION
Background: the rehabilitation nurses are decisive to the promotion of accessibility trough architectural barriers elimination, which promotes the reintegration of people with reduced mobility.
Rute Salomé da Silva Pereira+4 more
doaj +1 more source
The induction of transplantation tolerance is one of the primary goals following solid organ transplantation. The combination of a single dose of rapamycin (RAPA) with a short course of cyclosporine (CsA) has been shown to induce transplantation ...
W. Goggins+9 more
semanticscholar +1 more source
The Adaptation of the Buddhist Death Acceptance Scale for Vietnamese Persons with Cancer
Purpose: This study reports on selected psychometric properties of the adapted Buddhist Death Acceptance Scale (BDAS) for Vietnamese persons with cancer.
Nguyen H. Long, Sureeporn Thanasilp
doaj
Chronic rejection: insights from a novel immunosuppressive-free model of kidney transplantation.
The use of immunosuppressive drugs in models of chronic rejection may limit their usefulness for mechanistic studies. We have developed a new minor histocompatibility-mismatched rat kidney transplant model without the need for immunosuppression.
M. Gasser+6 more
semanticscholar +1 more source
Changes in drought features at the European level over the last 120 years
. In this study we analyze drought features at the European level over the period 1901–2019 using three drought indices: the standardized precipitation index (SPI), the standardized precipitation evapotranspiration index (SPEI), and the self-calibrated ...
M. Ionita, V. Nagavciuc
semanticscholar +1 more source
than one prior line of RT therapy and allogeneic stem cell transplantation up to 100 days prior to screening. Each treatment cycle (à 21 days) consists of one infusion of 200 mg tislelizumab at day 1 and 160 mg zanubrutinib twice daily orally. Six cycles
O. Al-Sawaf+17 more
semanticscholar +1 more source
Plants’ adaptations, in combination with the rhizosphere and endosphere microbiome, ensure their survival in the extreme conditions of the Antarctic. The work aimed to quantify the culturable microorganisms of different groups and establish the plant ...
Olga Maslovska+4 more
doaj +1 more source