Results 41 to 50 of about 881,713 (169)

Liderança tóxica, silêncio organizacional e engajamento com o trabalho de enfermeiros: Análise da modelagem de equação estrutural [PDF]

Acta Paulista de Enfermagem
Resumo Objetivo Investigar a influência da liderança tóxica dos gerentes e do silêncio organizacional no engajamento com o trabalho de enfermeiros usando modelagem de equações estruturais.
Donglian Zheng, Shuping Guo, Yan Wang, Na Liu, Fuzhen Ma   +4 more
doaj   +1 more source

Ideal soft tissue graft in periodontal and peri‐implant applications: A scoping review

Periodontology 2000, EarlyView.
Abstract Soft tissue grafts (STG) are used in a wide range of clinical situations including volume augmentation, keratinized tissue increase, and recession coverage around teeth and implants. Each STG, produced from different sources and processed with various techniques, possesses unique material properties and interaction with the host tissues, which
Madeline Yon, Elena Calciolari, Nikos Mardas, Anton Sculean, Nikolaos Donos   +4 more
wiley   +1 more source

Reliability and Validation Study of the Spanish Translation of the Nociception Coma Scale-Revised—Adapted for Intubated Patients (NCS-R-I)

Nursing Reports
Background/Objectives: Pain assessment scales provide a clear clinical benefit in patients who are unable to self-report. The Nociception Coma Scale-Revised—adapted for Intubated patients (NCS-R-I) was developed to assess pain in patients with acquired ...
Candelas López-López, Gemma Robleda-Font, María del Mar Sánchez-Sánchez, Carmen María Sarabia-Cobo, Ignacio Latorre-Marco, Montserrat Solís-Muñoz, Teresa Pérez-Pérez, Cristina Martín-Arriscado Arroba, Caroline Schnakers, Juan Roldan-Merino   +9 more
doaj   +1 more source

Several Initiatives but Little Results: A Novel Approach to Offer an Institutional Explanation for Food Insecurity in Ghana

World Food Policy, Volume 11, Issue 2, November 2025.
ABSTRACT A key strategy for achieving food security in Ghana is the implementation of food security projects. Unfortunately, one‐third of these projects encounter failure, primarily due to institutional shortcomings. The study demonstrates that institutional weaknesses are significant barriers to attaining food security and examines how institutional ...
Collins Oduro, Alan Renwick, Joseph Oscar Akotey   +2 more
wiley   +1 more source

Boosted Genomic Literacy in Nursing Students via Standardized-Patient Clinical Simulation: A Mixed-Methods Study

Nursing Reports
Background: Genomic information is becoming integral to nursing practice, yet undergraduate curricula often provide limited opportunities to apply this knowledge in realistic settings.
Daniel Garcia-Gutiérrez, Estel·la Ramírez-Baraldes, Maria Orera, Verónica Seidel, Carmen Martínez, Cristina García-Salido   +5 more
doaj   +1 more source

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.

Cancer Discovery, 2019
ATP-competitive Fibroblast Growth Factor Receptor (FGFR) kinase inhibitors, including BGJ398 and Debio1347, show antitumor activity in patients with intrahepatic cholangiocarcinoma (ICC) harboring activating FGFR2 gene fusions.
L. Goyal, Lei Shi, Leah Y. Liu, F. Fece de la Cruz, Jochen K. Lennerz, Srivatsan Raghavan, Ignaty Leschiner, Liudmila Elagina, G. Siravegna, Raymond W. S. Ng, P. Vu, K. Patra, Supriya K. Saha, R. Uppot, Ron Arellano, Stephanie Reyes, T. Sagara, S. Otsuki, Brandon Nadres, Heather A. Shahzade, I. Dey‐Guha, Isobel J. Fetter, I. Baiev, Emily E. Van Seventer, Janet E. Murphy, C. Ferrone, Kenneth K. Tanabe, V. Deshpande, J. Harding, R. Yaeger, R. Kelley, A. Bardelli, A. Iafrate, William C. Hahn, C. Benes, David T. Ting, H. Hirai, G. Getz, D. Juric, Andrew X. Zhu, R. Corcoran, N. Bardeesy   +41 more
semanticscholar   +1 more source

Mitochondrial Dysfunction in Neurodegenerative Diseases

MedComm, Volume 6, Issue 9, September 2025.
Overview of mitochondrial dysfunction in neurodegenerative diseases (NDDs). Mitochondrial dysfunction in NDDs involves impaired ATP synthesis, Ca2+ imbalance, oxidative stress, and apoptosis. Assessment methods integrate functional assays, omics, and imaging.
Chongyang Chen, Yujie Zhao, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Ming Lu, Gong‐Ping Liu   +10 more
wiley   +1 more source

Transforming Communication and Non-Technical Skills in Intermediate Care Nurses Through Ultra-Realistic Clinical Simulation: A Cross-Sectional Study

Nursing Reports
Background: Intermediate care units face growing complexity due to aging populations and chronic illnesses. Non-technical skills such as empathy and communication are crucial for quality care.
Mireia Adell-Lleixà, Francesc Riba-Porquet, Laia Grau-Castell, Lidia Sarrió-Colás, Marta Ginovart-Prieto, Elisa Mulet-Aloras, Silvia Reverté-Villarroya   +6 more
doaj   +1 more source

Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers

ACS Medicinal Chemistry Letters, 2018
Somatic point mutations at a key arginine residue (R132) within the active site of the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) confer a novel gain of function in cancer cells, resulting in the production of d-2-hydroxyglutarate (2-HG), an ...
Janeta Popovici-Muller, R. Lemieux, Erin Artin, J. Saunders, F. Salituro, J. Travins, Giovanni Cianchetta, Z. Cai, Ding Zhou, D. Cui, Ping Chen, K. Straley, E. Tobin, F. Wang, M. David, V. Penard-Lacronique, C. Quivoron, V. Saada, S. de Botton, S. Gross, L. Dang, Hua Yang, L. Utley, Yue Chen, HyeRyun Kim, Shengfang Jin, Zhiwei Gu, Gui Yao, Zhiyong Luo, Xiaobing Lv, Cheng Fang, Liping Yan, A. Olaharski, L. Silverman, S. Biller, Shinsan M. Su, K. Yen   +36 more
semanticscholar   +1 more source

How Do We Keep Our New Graduate Nurses in Australia?

Nursing Reports
This paper aims to discuss the transition of new graduate nurses into the workforce, the preparation provided to equip them through the novice–beginner stage, and the theory–practice conundrum.
Linda Ng, Rob Eley, Jennifer Dawson, Priya Govindaswamy, Karen Walker   +4 more
doaj   +1 more source