Diagnosis and Monitoring Pathways Using Non-Invasive Tests in Patients With Alpha-1 Antitrypsin Deficiency-Associated Liver Disease: Results From an Expert Delphi Panel. [PDF]
ABSTRACT Background and Aims The severe alpha‐1 antitrypsin deficiency (AATD) genotype Pi*ZZ increases the risk of liver disease (AATD‐LD) and lung disease. While non‐invasive tests (NITs) are widely used for fibrosis stage and monitoring of all liver diseases, the consensus for use in AATD‐LD is limited.
Clark VC +5 more
europepmc +2 more sources
"Someday, I'll be an ancestor:" Understanding indigenous intergenerational connectedness through qualitative research to inform measure development. [PDF]
Abstract Intergenerational connectedness broadly encompasses relations among humans, lands, and all living and spiritual beings, and functions as an important part of Indigenous well‐being. Many public health campaigns and interventions aim to promote connectedness to support holistic wellness and reduce health inequities. Currently, however, there are
O'Keefe VM +13 more
europepmc +2 more sources
Commercial-off-the-shelf simulation package interoperability: Issues and futures [PDF]
Commercial-Off-The-Shelf Simulation Packages (CSPs) are widely used in industry to simulate discrete-event models. Interoperability of CSPs requires the use of distributed simulation techniques.
A. Dunkin +9 more
core +2 more sources
The modular synthesis of rare earth-transition metal heterobimetallic complexes utilizing a redox-active ligand [PDF]
We report a robust and modular synthetic route to heterometallic rare earth-transition metal complexes. We have used the redox-active bridging ligand 1,10-phenathroline-5,6-dione (pd), which has selective N,N′ or O,O′ binding sites as the template for ...
Bamforth, Christopher +6 more
core +1 more source
ABSTRACT Despite the emphasis in sustainable development goals (SDG) 11, 13, and 17 on collaborative efforts to address climate change‐induced disaster risks through inclusive planning, stakeholders' role in fostering community engagement in risk‐sensitive urban planning (RSUP) remains underexplored.
Devindi Geekiyanage +2 more
wiley +1 more source
Advanced Message Routing for Scalable Distributed Simulations [PDF]
The Joint Forces Command (JFCOM) Experimentation Directorate (J9)'s recent Joint Urban Operations (JUO) experiments have demonstrated the viability of Forces Modeling and Simulation in a distributed environment.
Barrett, Brian, Gottschalk, Thomas
core
Abstract The incidence of Alzheimer's disease (AD) continues to increase, despite decades of effort to develop disease‐modifying therapies. In response, the National Institute on Aging (NIA) established the TaRget Enablement to Accelerate Therapy Development for Alzheimer's Disease (TREAT‐AD) centers to address the gap between basic research and ...
Timothy I. Richardson +8 more
wiley +1 more source
Planar Cooperative Extremum Seeking with Guaranteed Convergence Using A Three-Robot Formation
In this paper, a combined formation acquisition and cooperative extremum seeking control scheme is proposed for a team of three robots moving on a plane.
Fidan, Baris +3 more
core +1 more source
Design and Implementation of a FPGA and DSP Based MIMO Radar Imaging System [PDF]
The work presented in this paper is aimed at the implementation of a real-time multiple-input multiple-output (MIMO) imaging radar used for area surveillance.
Dong Liang +4 more
core +2 more sources
Evaluation of ASC as a therapeutic target for Alzheimer's disease
Abstract Neuroinflammation is increasingly recognized as a central contributor to the pathogenesis and progression of Alzheimer's disease (AD). The apoptosis‐associated speck‐like protein containing a CARD (ASC), encoded by the PYCARD gene, plays a critical role in the formation of multiple inflammasomes, including NLRP3, a key mediator of inflammation
W. Brent Clayton +12 more
wiley +1 more source

