Results 41 to 50 of about 78,524 (254)

Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data. [PDF]

, 2013
BACKGROUND: The efficacy of RTS,S/AS01 as a vaccine for malaria is being tested in a phase 3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria and severe malaria.
Abdulla, Salim, Ghani, Azra C, Asante, Kwaku Poku, White, Michael T, Owusu-Agyei, Seth, Lusingu, John PA, Bejon, Philip, Agnandji, Selidji T, Otsyula, Nekoye N, Olotu, Ally, Bojang, Kalifa, Salim, Nahya   +11 more
core   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection. [PDF]

, 2006
OBJECTIVE: The candidate malaria vaccine RTS,S/AS02A is a recombinant protein containing part of the circumsporozoite protein (CSP) sequence of Plasmodium falciparum, linked to the hepatitis B surface antigen and formulated in the proprietary adjuvant ...
Dobaño, Carlota, 1969-, Sacarlal, Jahit, Conway, David J, Quelhas, Diana, Conway David J, Thompson Ricardo, Sutherland Colin J, Conway, David J., Alonso Pedro L, Quelhas Diana, Ballou W. Ripley, Aponte, John J., Cohen Joe, Dobaño, Carlota, Sutherland, Colin J, Lievens Marc, Dobaño Carlota, Leach, Amanda, Greenwood, Brian, Aponte John J, Alonso, Pedro, Milman Jessica, Cohen, Joe, Enosse, Sonia, Sacarlal Jahit, Greenwood Brian, Aponte, John J, Dubovsky, Filip, Sutherland, Colin J., Ballou, W Ripley, Ballou, W. Ripley, Enosse Sonia, Lievens, Marc, Alonso, Pedro L, Leach Amanda, Dubovsky Filip, Milman, Jessica, Thompson, Ricardo   +37 more
core   +1 more source

Mapping the Social Network Structure and Composition of Black Individuals With Rheumatic and Musculoskeletal Conditions

Arthritis Care &Research, EarlyView.
Objective Our objective was to describe the social networks of Black individuals with rheumatic and musculoskeletal conditions and understand the clustering of health‐related behaviors to inform future community‐based, peer‐led interventions. Methods We used an adapted Personal Network Survey for Clinical Research (PERSNET) to map the personal social ...
Taussia Boadi, Amar Dhand, Leah Santacroce, Neil Pillai, Komel Safdar, Mia T. Chandler, Ariel Childs, Monica Crespo‐Bosque, Gina Curry, Mary Dollear, Alice Eggleston, Daniel Erickson, Dieufort Fleurissaint, Denice Garrett, Gail Granville, Tyler Green, Magdalena Hamielec, Elena Losina, Karen Mancera‐Cuevas, Mary Ann Nelson, Chisa Nosamiefan, Bisola Ojikutu, Tonya S. Roberson, Mary Beth Son, Marie Jacques Toussaint, Michael York, Rosalind Ramsey‐Goldman, Candace H. Feldman   +27 more
wiley   +1 more source

Effect of Nitrogen Doping on the Proton‐Irradiation Stability of Carbon Nanowalls

Advanced Materials Interfaces, EarlyView.
Proton irradiation effects in carbon nanowalls are systematically compared with nitrogen‐doped counterparts over a wide fluence range. While both systems maintain structural integrity, nitrogen incorporation alters the functional response under irradiation.
Baglan A. Kyrykbay, Rakhymzhan Ye. Zhumadilov, Renata R. Nemkayeva, Bauyrzhan Ye. Zhumadilov, Gulnur Akhtanova, Hryhorii Parkhomenko, Alexander V. Kireyev, Sagi A. Orazbayev, Tlekkabul S. Ramazanov, Maratbek T. Gabdullin, Askhat N. Jumabekov, Viktor V. Brus, Yerassyl Yerlanuly   +12 more
wiley   +1 more source

EPD of Finnish sawn and planed timber [PDF]

, 2021
This environmental product declaration (EPD) is for sawn and planed softwood timber produced by member companies of the Finnish Sawmills Association. The declaration has been prepared in accordance with standard EN 15804:2019 + A2 and RTS PCR (version 1 ...
Räty, Tarmo, Jallinoja, Marja
core  

Dipolar Coupling Errors in Nuclear Spin Qubits

Advanced Science, EarlyView.
Multi‐nuclear spin registers of phosphorus‐atom qubits in silicon have demonstrated 99.99% single and >$>$99.9% two qubit gate fidelities. Despite nanometer separation, read‐out fidelities between individual nuclear spins within the register are not identical.
I. D. Thorvaldson, P. Macha, J. Reiner, S. H. Misha, Y. Chung, L. Kranz, D. Keith, S. Monir, D. Poulos, S. Sutherland, Y.‐L. Hsueh, B. Thorgrimsson, R. Rahman, J. G. Keizer, S. K. Gorman, M. Y. Simmons   +15 more
wiley   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

Advanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau, John J. Foxe, Shlomit Beker, Sophie Molholm   +3 more
wiley   +1 more source

Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS,S/AS01 administered with dihydroartemisinin, piperaquine, and primaquine in healthy Thai adult volunteers

Human Vaccines & Immunotherapeutics, 2020
Introduction: RTS,S/AS01 is currently the most advanced malaria vaccine but provides incomplete, short-term protection. It was developed for use within the expanded program on immunizations (EPI) for African children. Another use could be adding mass RTS,
Lorenz von Seidlein, Borimas Hanboonkunupakarn, Podjanee Jittamala, Pongphaya Pongsuwan, Kesinee Chotivanich, Joel Tarning, Richard M. Hoglund, Markus Winterberg, Mavuto Mukaka, Pimnara Peerawaranun, Pasathorn Sirithiranont, Zoe Doran, Christian F. Ockenhouse, Karen Ivinson, Cynthia Lee, Ashley J. Birkett, David C. Kaslow, Pratap Singhasivanon, Nicholas P.J. Day, Arjen M. Dondorp, Nicholas J. White, Sasithon Pukrittayakamee   +21 more
doaj   +1 more source

Deforestation and Efficiency: Insights From Forest Transition in the Brazilian Cerrado

Agribusiness, EarlyView.
ABSTRACT This paper estimates technical efficiency (TE) and environmental efficiency (EE) of agricultural production at the municipal level of the Brazilian Cerrado in 2006 and 2017, and investigates their underlying mechanisms in relation to forest transition theory.
Ricardo Muniz Simões, Cassiano Bragagnolo, Humberto Francisco Silva Spolador   +2 more
wiley   +1 more source