Results 81 to 90 of about 42,664 (203)
ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley +1 more source
A tomato MIK2‐clade receptor is involved in the perception of a Fusarium‐derived elicitor
Fusarium elicitor responsivness and MIK2‐clade proteins are conserved across plant families. Summary Plants continuously monitor their environment to adapt to threats affecting health and fitness. Cell‐surface receptors detect conserved microbe‐associated molecular patterns (MAMPs) or endogenous immunogenic signals to activate signaling pathways that ...
Julian Maroschek +6 more
wiley +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi +6 more
wiley +1 more source
ABSTRACT Background and Aims Hepatitis B virus (HBV) infection is a significant chronic infection in pediatric patients. Vaccination induces production of anti‐Hepatitis B surface antibodies, which serve as markers of protective immunity. Given the long‐term risks of cirrhosis and hepatocellular carcinoma during adulthood, this study aimed to assess ...
Erfanehsadat Shahim +7 more
wiley +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Abstract Problem Maternal obesity and viral infection induce placental inflammation, but how their co‐exposure influence fetoplacental development remains unclear. We hypothesised that maternal high fat (HF) diet and viral infection would independently induce placental inflammation and lipid peroxidation, reduce antioxidant defence, and cellular ...
Thaina Ferraz +4 more
wiley +1 more source
Strengthening Australia's research integrity system
Abstract Misconduct in research is a serious issue and is probably increasing. To grapple fully with this, to protect the reputation of honest researchers and to improve public accountability, the Australian research integrity system needs strengthening. The Australian Code for the Responsible Conduct of Research must be revised to mandate how research
Warwick Anderson, Kerry Breen
wiley +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source

