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Rubella virus perturbs autophagy
Medical Microbiology and Immunology, 2014Autophagy is a cellular catabolic process implicated in numerous physiological processes and pathological conditions, including infections. Viruses have evolved different strategies to modulate the autophagic process. Since the effects of rubella virus (RV) on autophagy have not yet been reported, we evaluated the autophagic activity in the Statens ...
Pásztor Kata +3 more
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Glycopolypeptides of rubella virus
Archives of Virology, 1983Purified rubella virus particles contain two glycopolypeptides (62K and 44K to 51K) and one nonglycosylated polypeptide (35K). Glycoproteins can be labeled with tritiated sodiumborohydride after oxidation with galactose oxidase indicating that galactose is the terminal carbohydrate unit.
Raija Vainionpää +3 more
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The structural proteins of rubella virus
Virology, 1972Abstract Purified rubella virus was reduced in the presence of 4 M urea, 50 m M DTT, and 2% SDS and carboxymethylated with iodoacetate. The resulting polypeptides were separated by electrophoresis in 20 cm neutral-SDS 5% polyacrylamide gels containing 4 M urea and 2 m M DTT, into 3 major electrophoretic zones containing 8 species of partially ...
Harvey Liebhaber, Peter A. Gross
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Hemolytic activity of rubella virus
Virology, 1978Abstract Hemolytic activity of rubella virus was demonstrated by chelating Ca2+ with EDTA after adsorption of the virus to erythrocytes in the presence of the ion. The hemolysis was inhibited by rabbit serum immunized with the virus. Furthermore, the hemolytic activity co-sedimented in sucrose density gradient centrifugation with the hemagglutinating
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Biological characteristics of rubella virus
Archiv f�r die gesamte Virusforschung, 1965A virus, recognized by its ability to interfere in GMK cultures with the CPE of E-11 virus, was recovered from patients with rubella. This virus differed from other human viruses in both biologic and serologic characteristics, and appears on the basis of these combined laboratory and epidemiologic observations to be the etiologic agent of rubella.
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Seroimmunity to rubella virus in Jordanians
Public Health, 1983Abstract Sera of 985 Jordanians from 1 to 36 years of age and 115 cord blood specimens werescreened for rubella haemagglutination-inhibition antibodies. The percentage of seropositivity increased with age, 73–76% of the younger group were positive, while 80–91% of the older group and 95% of cord blood specimens were positive. Analysis of the results
Sa'ad Hijazi +3 more
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Physical Characteristics of Rubella Virus
The Journal of Immunology, 1969Summary Rubella virus centrifuged over a preformed CsCl gradient for 1.5 hr gave a sharp, opaque band at a density of 1.22. Recovery of infectivity and hemagglutinin from crude suspensions was almost complete. Electron microscopic examination of the band showed structured particles averaging 55 mµ in diameter (range was 42 to 71 mµ ...
K O, Smith, T E, Hobbins
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Rubella Virus: Direct Fluorescence
American Journal of Clinical Pathology, 1967The laboratory diagnosis of German measles can be accomplished by several methods. One method involves the ability of rubella virus to render African green monkey kidney (AGMK) cell cultures resistant to infection with enteroviruses. Another method utilizes the indirect fluorescent technic; with it infections due to rubella virus are recognized in ...
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IMMUNOGLOBULINS AND RUBELLA-VIRUS ANTIBODIES IN ADULTS WITH CONGENITAL RUBELLA
The Lancet, 1968Abstract Fifty adults with congenital rubella were compared with blood-donors of the same age, sex, and racial background with respect to serum-immunoglobulin levels and rubella-virus haemagglutination-inhibition antibody (H.I.) titres. All rubella patients were well when tested and none had a history of an abnormal incidence of intercurrent infection.
RobynF. Slinn +3 more
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Rubella Virus–Induced Diabetes in the Hamster
Diabetes, 1986The congenital rubella syndrome provides the best documentation in humans that a viral infection is associated with the subsequent development of insulin-dependent diabetes mellitus. We have developed an animal model in neonatal golden Syrian hamsters infected with rubella virus passaged in β-cells that closely parallels the diabetes observed with ...
E J Rayfield +2 more
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