Results 91 to 100 of about 722 (280)

Photonic integration of an optical atomic clock

open access: yes, 2018
Laboratory optical atomic clocks achieve remarkable accuracy (now counted to 18 digits or more), opening possibilities to explore fundamental physics and enable new measurements. However, their size and use of bulk components prevent them from being more
K. Y. Yang (17473173)   +21 more
core   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Comparative Study of Satellite Clock Bias Prediction Models Based on Genetic Algorithm and Mind Evolutionary Algorithm-Optimized BP Neural Networks

open access: yesApplied Sciences
Satellite clock bias (SCB) is a critical error source affecting the positioning and timing accuracy of Global Navigation Satellite Systems (GNSSs). The conventional back propagation neural network (BP) model, when applied to SCB prediction, is prone to ...
Hongwei Bai   +3 more
doaj   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui   +14 more
wiley   +1 more source

Production of Miniature Glass Cells with Rubidium for Chip Scale Atomic Clock

open access: yesPhysics Procedia, 2015
AbstractThe main advantage of chip scale atomic clock (e.g., Knappe (2008)) (CSAC) over quartz-oscillators is the higher long-term stability. It is provided by non-aging resonance of unperturbed atoms. However it is not a simple task to suppress all possible perturbations.
Losev, S.S.   +3 more
openaire   +1 more source

Design a Robust Control System for Rubidium Fountain Clock

open access: yes
Rubidium fountain clocks are operated by a control system. In this study, first, the control requirements of a rubidium fountain clock are analyzed; then, a control system is designed and divided into a timing sequence control system, a data acquisition ...
Jun Ruan   +5 more
core   +1 more source

Coherent Control of Entanglement with Atomic Ensembles [PDF]

open access: yes, 2011
Quantum networks are composed of quantum nodes which coherently interact by way of quantum channels. They offer powerful capabilities for quantum computation, communication, and metrology. A generic requirement for these realizations is the capability to
Choi, Kyung Soo
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

open access: yesAdvanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong   +7 more
wiley   +1 more source

An optical atomic clock using $4D_J$ states of rubidium

open access: yes
A.D. and C.O.
Duspayev, Alisher   +3 more
openaire   +2 more sources

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