Results 121 to 130 of about 4,787 (279)
Advanced Science, EarlyView.It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló +2 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao +9 more
wiley +1 more source
Advanced Science, EarlyView.High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy
Advanced Science, EarlyView.The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling +9 more
wiley +1 more source
Atomic frequency standards for ultra-high-frequency stability [PDF]
The general features of the Hg-199(+) trapped-ion frequency standard are outlined and compared to other atomic frequency standards, especially the hydrogen maser.
Dick, G. J., Maleki, L., Prestage, J. D.
core +1 more source
Advanced Science, EarlyView.Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej +10 more
wiley +1 more source
Microfabricated rubidium dielectric barrier discharge light sources for portable atomic clocks
, 2013 Keywords: atomic clocks ; rubidium ; dielectric barrier discharge ; microfabrication ; anodic bonding ; rf plasma ; solder sealing ; double-resonance These Ecole polytechnique federale de Lausanne EPFL, n° 5702 (2013)Programme doctoral Microsystemes et MicroelectroniqueFaculte des sciences et techniques de l'ingenieurInstitut de ...
openaire +1 more source
GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer
Advanced Science, EarlyView.Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello +10 more
wiley +1 more source
Advanced Science, EarlyView.Nanodiamond additives are dispersed in the aqueous electrolyte to organize water molecules, suppress gas evolution and metal corrosion, and guide zinc to deposit more uniformly. Together with enhanced thermal conductivity for fast heat removal, this strategy reduces temperature rise and degradation, enabling safer, more durable rechargeable zinc metal ...
Jiayan Zhu +7 more
wiley +1 more source
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source