Results 211 to 220 of about 722 (280)

Picosecond synchronization of mode-locked lasers for metropolitan-scale quantum networks. [PDF]

open access: yesOpt Express
Nunn C   +6 more
europepmc   +1 more source

Modulation of the Stress Granule Component Carhsp1 Mitigates Disease‐Associated Deficits in Spinocerebellar Ataxia Type 3 Mouse Models

open access: yesMovement Disorders, EarlyView.
Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes   +9 more
wiley   +1 more source

CLEC14A correlates with neutrophil infiltration in hepatocellular carcinoma and mediates neutrophil recruitment across liver endothelial cells

open access: yesThe Journal of Pathology, EarlyView.
Abstract Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related deaths globally, and cases are predicted to rise dramatically over the next few years. Overcoming the immune microenvironment in HCC remains a challenge, and innate immune populations such as tumour‐associated neutrophils can potentially impair the success of immunotherapy ...
Joanne M O'Rourke   +24 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Multiproxy Chronologies of the Hurd Rock Glacier (Livingston Island, South Shetland Islands, Maritime Antarctica): Between the Late‐Stage Stabilization and Flow Deceleration

open access: yesPermafrost and Periglacial Processes, EarlyView.
ABSTRACT The Hurd Rock Glacier, located on Livingston Island (South Shetland Islands archipelago, Maritime Antarctica), is a tongue‐shaped feature composed of angular boulders, displaying transverse ridges and furrows, and featuring lobate structures, which are more prominently developed in its frontal sector.
Rosana Menéndez‐Duarte   +5 more
wiley   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

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