Results 41 to 50 of about 4,797 (280)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A mathematical model for the atomic clock error in case of jumps

, 2015
We extend the mathematical model based on stochastic differential equations describing the error gained by an atomic clock to the cases of anomalous behavior including jumps and an increase of instability. We prove an exact iterative solution that can be
Tavella, Patrizia, Zucca, Cristina
core   +1 more source

Coherent manipulation of atomic qubits in optical micropotentials [PDF]

, 2007
We experimentally demonstrate the coherent manipulation of atomic states in far-detuned dipole traps and registers of dipole traps based on two-dimensional arrays of microlenses.
A. Kaplan, A. Lengwenus, C. Klempt, E.L. Hahn, F. Bloch, F.B.J. Buchkremer, G. Birkl, G. Birkl, G. Grynberg, H. Katori, I. Deutsch, J. Kruse, M. Volk, M.A. Nielsen, M.F. Andersen, N. Davidson, N. Schlosser, N.A. Kurnit, N.F. Ramsey, P. Treutlein, P.S. Jessen, R. Dumke, R. Ozeri, S. Kuhr, W. Ertmer   +24 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Alkali Vapor MEMS Cells Technology toward High-Vacuum Self-Pumping MEMS Cell for Atomic Spectroscopy

Micromachines, 2018
The high-vacuum self-pumping MEMS cell for atomic spectroscopy presented here is the result of the technological achievements of the author and the research group in which he works.
Pawel Knapkiewicz
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Evaluation of Long Term Performance of Continuously Running Atomic Fountains

, 2014
An ensemble of rubidium atomic fountain clocks has been put into operation at the U.S. Naval Observatory (USNO). These fountains are used as continuous clocks in the manner of commercial cesium beams and hydrogen masers for the purpose of improved timing
Ekstrom, Christopher R., Hanssen, James L., Peil, Steven, Swanson, Thomas B., Taylor, Jennifer   +4 more
core   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Electromagnetic Separation of High-abundance Rubidium-87 and Its Application

Journal of Isotopes
The rubidium clock，as the core part of the Beidou satellite navigation and positioning system，mainly provides high-precision time reference signals. Its accuracy will directly affect the performance of the Beidou system.
Li LONG, Xiuyan REN, Dan WU, Bo YUAN, Suxu LIU   +4 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source