Results 51 to 60 of about 4,135 (178)
Paramyxovirus V proteins interact with the RNA helicase LGP2 to inhibit RIG-I-dependent interferon induction [PDF]
, 2012 This work was supported by the Wellcome Trust (grant AL087751/B)RIG-I and mda-5 are activated by viral RNA and stimulate type I interferon production. Laboratory of genetics and physiology 2 (LGP2) shares homology with RIG-I and mda-5 but lacks the CARD ...
Childs, Kay +2 more
core +1 more source
From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis
Microbial Biotechnology, Volume 18, Issue 7, July 2025.Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley +1 more source
Type I Diabetes Mellitus: Genetic Factors and Presumptive Enteroviral Etiology or Protection
Journal of Pathogens, Volume 2014, Issue 1, 2014., 2014 We review type 1 diabetes and host genetic components, as well as epigenetics and viruses associated with type 1 diabetes, with added emphasis on the enteroviruses, which are often associated with triggering the disease. Genus Enterovirus is classified into twelve species of which seven (Enterovirus A, Enterovirus B, Enterovirus C, and Enterovirus D ...
Jana Precechtelova +4 more
wiley +1 more source
Within host RNA virus persistence : mechanisms and consequences [PDF]
, 2017 RER is funded by the Wellcome Trust, UK (Grant 101788/Z/13/Z) and DEG by US National Institutes of Health (R01 NS038932).In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all ...
Griffin, Diane E., Randall, Richard E.
core +1 more source
Protein Post‐Translational Modification‐Mediated Control of Type I Interferon Cascade Signaling
Medicine Bulletin, Volume 1, Issue 1, Page 37-59, June 2025.ABSTRACT Type I interferons (IFN‐Is) constitute the primary defense mechanism against pathogenic infections in the human body. The antiviral signaling mediated by IFN‐I is integral to the host immune response. Nevertheless, an imbalance in IFN‐I function can perturb the organism’s homeostasis. Consequently, it is imperative for the body to meticulously
Xiangjie Chen +3 more
wiley +1 more source
Veterinary Medicine International, Volume 2012, Issue 1, 2012., 2012 Avian paramyxovirus serotype‐1 (APMV‐1) is capable of infecting a wide range of avian species leading to a broad range of clinical symptoms. Ease of transmission has allowed the virus to spread worldwide with varying degrees of virulence depending on the virus strain and host species. Classification systems have been designed to group isolates based on
Nichole L. Hines +2 more
wiley +1 more source
Cloning and Expression of the Haemagglutinin-neuraminidase Gene of Newcastle Disease Virus Strain Af2240 Lnto Eschericia Coli [PDF]
, 1997 A 1815 bp sequence of the open reading frame (ORF) of the haemagglutinin-neuraminidase (HN) gene of velogenic-viscerotropic Newcastle disease virus (NDV) strain AF2240 was amplified reaction (PCR) using primers SI (5'CACCAATAGCAGACTCCA3') and S2 (5 ...
Sudin, Sudani
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Journal of Medical Virology, Volume 97, Issue 5, May 2025.ABSTRACT Human parainfluenza virus type 3 (HPIV‐3) can be responsible for mild to severe respiratory infections and hospital epidemics. We investigated an outbreak in a hematology unit. Respiratory viruses were screened using multiplex PCR. HPIV‐3 quantification and whole‐genome sequencing were performed on HPIV‐3 positive respiratory samples. Clinical
Sarah Timsit +13 more
wiley +1 more source
An Evaluation of Mumps Antibody Titers Among Pharmacy Students Before and After a University Mumps Outbreak [PDF]
, 2017 Mumps outbreaks continue to transpire across the United States despite the available MMR (Measles-Mumps-Rubella) vaccine and seemingly high vaccination rates. There is limited evidence surrounding the management, impact, and prevention of mumps outbreaks.
Shelley, Kiley
core +1 more source
A case report of serological evidence of paramyxoviruses related to Porcine orthorubulavirus in Mexican bats [PDF]
, 2022 In this report, we showed the presence of antibodies to Porcine orthorubulavirus (PRV) in Mexican bats using a serological approach. A total of 42 bats, belonging to seven different species, were sampled from two different refuges/caves, located near to ...
Berg, Mikael +2 more
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